Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classY
GeneSetPOSITIVE REGULATION OF LYASE ACTIVITY
Enrichment Score (ES)-0.56008637
Normalized Enrichment Score (NES)-1.8103123
Nominal p-value0.00407332
FDR q-value0.61437434
FWER p-Value0.913
Table: GSEA Results Summary



Fig 1: Enrichment plot: POSITIVE REGULATION OF LYASE ACTIVITY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FXNFXN
Entrez,  Source
frataxin8780.1520.0035No
2ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor20070.112-0.0174No
3CAP1CAP1
Entrez,  Source
CAP, adenylate cyclase-associated protein 1 (yeast)48300.054-0.1382No
4PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha53950.045-0.1520No
5VIPVIP
Entrez,  Source
vasoactive intestinal peptide69320.024-0.2193No
6EDNRAEDNRA
Entrez,  Source
endothelin receptor type A85320.004-0.2958No
7NOS3NOS3
Entrez,  Source
nitric oxide synthase 3 (endothelial cell)87390.002-0.3053No
8GNASGNAS
Entrez,  Source
GNAS complex locus8949-0.001-0.3152No
9NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)10093-0.013-0.3667No
10NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 210742-0.021-0.3919No
11ADORA2AADORA2A
Entrez,  Source
adenosine A2a receptor12918-0.045-0.4839No
12DRD1DRD1
Entrez,  Source
dopamine receptor D112921-0.045-0.4704No
13GLP1RGLP1R
Entrez,  Source
glucagon-like peptide 1 receptor14676-0.065-0.5360Yes
14ADCYAP1ADCYAP1
Entrez,  Source
adenylate cyclase activating polypeptide 1 (pituitary)14782-0.066-0.5210Yes
15DRD5DRD5
Entrez,  Source
dopamine receptor D515191-0.071-0.5193Yes
16GUCA1AGUCA1A
Entrez,  Source
guanylate cyclase activator 1A (retina)16032-0.083-0.5349Yes
17RCVRNRCVRN
Entrez,  Source
recoverin16460-0.089-0.5287Yes
18GUCA1CGUCA1C
Entrez,  Source
guanylate cyclase activator 1C16462-0.089-0.5018Yes
19LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor16890-0.095-0.4936Yes
20CALCRCALCR
Entrez,  Source
calcitonin receptor17044-0.098-0.4713Yes
21PARK7PARK7
Entrez,  Source
Parkinson disease (autosomal recessive, early onset) 717074-0.098-0.4429Yes
22ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor17471-0.105-0.4304Yes
23ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface18267-0.119-0.4328Yes
24CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)18305-0.120-0.3981Yes
25ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor18534-0.125-0.3711Yes
26ADCYAP1R1ADCYAP1R1
Entrez,  Source
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I18920-0.134-0.3491Yes
27AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)19482-0.152-0.3302Yes
28GUCA2BGUCA2B
Entrez,  Source
guanylate cyclase activator 2B (uroguanylin)19573-0.156-0.2872Yes
29ACRACR
Entrez,  Source
acrosin19701-0.161-0.2444Yes
30CRHR1CRHR1
Entrez,  Source
corticotropin releasing hormone receptor 119792-0.165-0.1987Yes
31CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha19817-0.167-0.1492Yes
32GIPRGIPR
Entrez,  Source
gastric inhibitory polypeptide receptor19823-0.167-0.0987Yes
33NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 120338-0.211-0.0596Yes
34P2RY11P2RY11
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 1120500-0.2390.0051Yes
Table: GSEA details [plain text format]



Fig 2: POSITIVE REGULATION OF LYASE ACTIVITY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: POSITIVE REGULATION OF LYASE ACTIVITY: Random ES distribution   
Gene set null distribution of ES for POSITIVE REGULATION OF LYASE ACTIVITY