Dataset | gse25507_collapsed_to_symbols.gse25507.gpl570.cls #N_versus_Y.gse25507.gpl570.cls #N_versus_Y_repos |
Phenotype | gse25507.gpl570.cls#N_versus_Y_repos |
Upregulated in class | N |
GeneSet | TRANSCRIPTION ELONGATION FROM RNA POLYMERASE II PROMOTER |
Enrichment Score (ES) | 0.58077013 |
Normalized Enrichment Score (NES) | 1.7817864 |
Nominal p-value | 0.009784736 |
FDR q-value | 1.0 |
FWER p-Value | 0.956 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | POLR2E | POLR2E Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | 46 | 0.257 | 0.0508 | Yes |
2 | GTF2H1 | GTF2H1 Entrez,  Source | general transcription factor IIH, polypeptide 1, 62kDa | 65 | 0.245 | 0.1005 | Yes |
3 | CCNT1 | CCNT1 Entrez,  Source | cyclin T1 | 580 | 0.170 | 0.1106 | Yes |
4 | TAF4 | TAF4 Entrez,  Source | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | 593 | 0.170 | 0.1450 | Yes |
5 | GTF2A1 | GTF2A1 Entrez,  Source | general transcription factor IIA, 1, 19/37kDa | 732 | 0.160 | 0.1712 | Yes |
6 | SUPT4H1 | SUPT4H1 Entrez,  Source | suppressor of Ty 4 homolog 1 (S. cerevisiae) | 818 | 0.155 | 0.1990 | Yes |
7 | TAF12 | TAF12 Entrez,  Source | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa | 854 | 0.153 | 0.2289 | Yes |
8 | TAF4B | TAF4B Entrez,  Source | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 899 | 0.151 | 0.2580 | Yes |
9 | TAF1 | TAF1 Entrez,  Source | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 1471 | 0.128 | 0.2566 | Yes |
10 | CCNT2 | CCNT2 Entrez,  Source | cyclin T2 | 1758 | 0.119 | 0.2672 | Yes |
11 | GTF2H2 | GTF2H2 Entrez,  Source | general transcription factor IIH, polypeptide 2, 44kDa | 1815 | 0.117 | 0.2886 | Yes |
12 | GTF2E1 | GTF2E1 Entrez,  Source | general transcription factor IIE, polypeptide 1, alpha 56kDa | 1822 | 0.117 | 0.3124 | Yes |
13 | TCEB1 | TCEB1 Entrez,  Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 1881 | 0.115 | 0.3333 | Yes |
14 | GTF2A2 | GTF2A2 Entrez,  Source | general transcription factor IIA, 2, 12kDa | 2020 | 0.111 | 0.3496 | Yes |
15 | GTF2H5 | GTF2H5 Entrez,  Source | general transcription factor IIH, polypeptide 5 | 2024 | 0.111 | 0.3723 | Yes |
16 | NCBP1 | NCBP1 Entrez,  Source | nuclear cap binding protein subunit 1, 80kDa | 2176 | 0.107 | 0.3870 | Yes |
17 | GTF2F2 | GTF2F2 Entrez,  Source | general transcription factor IIF, polypeptide 2, 30kDa | 2278 | 0.104 | 0.4036 | Yes |
18 | POLR2A | POLR2A Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 2536 | 0.098 | 0.4113 | Yes |
19 | POLR2K | POLR2K Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 2717 | 0.094 | 0.4219 | Yes |
20 | POLR2J | POLR2J Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | 2873 | 0.090 | 0.4330 | Yes |
21 | CCNK | CCNK Entrez,  Source | cyclin K | 3009 | 0.088 | 0.4445 | Yes |
22 | POLR2F | POLR2F Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide F | 3055 | 0.086 | 0.4601 | Yes |
23 | TAF9B | TAF9B Entrez,  Source | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 3098 | 0.085 | 0.4757 | Yes |
24 | TAF2 | TAF2 Entrez,  Source | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 3546 | 0.077 | 0.4698 | Yes |
25 | ELL | ELL Entrez,  Source | elongation factor RNA polymerase II | 3573 | 0.076 | 0.4843 | Yes |
26 | ERCC2 | ERCC2 Entrez,  Source | excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D) | 3774 | 0.072 | 0.4894 | Yes |
27 | GTF2F1 | GTF2F1 Entrez,  Source | general transcription factor IIF, polypeptide 1, 74kDa | 3923 | 0.069 | 0.4965 | Yes |
28 | GTF2B | GTF2B Entrez,  Source | general transcription factor IIB | 3954 | 0.069 | 0.5092 | Yes |
29 | CCNH | CCNH Entrez,  Source | cyclin H | 4053 | 0.067 | 0.5182 | Yes |
30 | ELP4 | ELP4 Entrez,  Source | elongation protein 4 homolog (S. cerevisiae) | 4196 | 0.064 | 0.5245 | Yes |
31 | TCEB2 | TCEB2 Entrez,  Source | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 4276 | 0.063 | 0.5336 | Yes |
32 | POLR2L | POLR2L Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 4543 | 0.058 | 0.5327 | Yes |
33 | TAF10 | TAF10 Entrez,  Source | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 4826 | 0.054 | 0.5301 | Yes |
34 | TAF6 | TAF6 Entrez,  Source | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa | 4844 | 0.054 | 0.5403 | Yes |
35 | ELL3 | ELL3 Entrez,  Source | elongation factor RNA polymerase II-like 3 | 4876 | 0.053 | 0.5498 | Yes |
36 | SETD2 | SETD2 Entrez,  Source | SET domain containing 2 | 4906 | 0.053 | 0.5592 | Yes |
37 | TAF5 | TAF5 Entrez,  Source | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa | 5002 | 0.051 | 0.5651 | Yes |
38 | POLR2C | POLR2C Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 5054 | 0.050 | 0.5731 | Yes |
39 | ELP3 | ELP3 Entrez,  Source | elongation protein 3 homolog (S. cerevisiae) | 5107 | 0.050 | 0.5808 | Yes |
40 | TAF13 | TAF13 Entrez,  Source | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa | 6147 | 0.034 | 0.5373 | No |
41 | TCEA1 | TCEA1 Entrez,  Source | transcription elongation factor A (SII), 1 | 6148 | 0.034 | 0.5444 | No |
42 | ADRM1 | ADRM1 Entrez,  Source | adhesion regulating molecule 1 | 6590 | 0.029 | 0.5289 | No |
43 | POLR2G | POLR2G Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide G | 6689 | 0.028 | 0.5298 | No |
44 | TCEB3 | TCEB3 Entrez,  Source | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | 6690 | 0.028 | 0.5354 | No |
45 | TAF9 | TAF9 Entrez,  Source | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 7225 | 0.021 | 0.5137 | No |
46 | NCBP2 | NCBP2 Entrez,  Source | nuclear cap binding protein subunit 2, 20kDa | 7415 | 0.018 | 0.5082 | No |
47 | CDK7 | CDK7 Entrez,  Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 7465 | 0.017 | 0.5094 | No |
48 | TAF1L | TAF1L Entrez,  Source | TAF1-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa | 7527 | 0.017 | 0.5099 | No |
49 | TBP | TBP Entrez,  Source | TATA box binding protein | 7864 | 0.013 | 0.4961 | No |
50 | GTF2E2 | GTF2E2 Entrez,  Source | general transcription factor IIE, polypeptide 2, beta 34kDa | 8810 | 0.001 | 0.4502 | No |
51 | TAF11 | TAF11 Entrez,  Source | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | 8968 | -0.001 | 0.4428 | No |
52 | TAF3 | TAF3 Entrez,  Source | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa | 9308 | -0.005 | 0.4273 | No |
53 | CDK9 | CDK9 Entrez,  Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 9804 | -0.010 | 0.4053 | No |
54 | POLR2I | POLR2I Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 9918 | -0.011 | 0.4021 | No |
55 | SUPT16H | SUPT16H Entrez,  Source | suppressor of Ty 16 homolog (S. cerevisiae) | 10599 | -0.019 | 0.3729 | No |
56 | POLR2B | POLR2B Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 11503 | -0.029 | 0.3350 | No |
57 | CTDP1 | CTDP1 Entrez,  Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 11672 | -0.031 | 0.3333 | No |
58 | ERCC3 | ERCC3 Entrez,  Source | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 11903 | -0.034 | 0.3291 | No |
59 | POLR2D | POLR2D Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide D | 12363 | -0.039 | 0.3147 | No |
60 | SUPT5H | SUPT5H Entrez,  Source | suppressor of Ty 5 homolog (S. cerevisiae) | 12680 | -0.042 | 0.3080 | No |
61 | SSRP1 | SSRP1 Entrez,  Source | structure specific recognition protein 1 | 13082 | -0.047 | 0.2981 | No |
62 | IKBKAP | IKBKAP Entrez,  Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein | 13171 | -0.048 | 0.3036 | No |
63 | MNAT1 | MNAT1 Entrez,  Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 13415 | -0.050 | 0.3021 | No |
64 | GTF2H4 | GTF2H4 Entrez,  Source | general transcription factor IIH, polypeptide 4, 52kDa | 13858 | -0.055 | 0.2920 | No |
65 | GTF2H3 | GTF2H3 Entrez,  Source | general transcription factor IIH, polypeptide 3, 34kDa | 14071 | -0.058 | 0.2936 | No |
66 | POLR2H | POLR2H Entrez,  Source | polymerase (RNA) II (DNA directed) polypeptide H | 18231 | -0.119 | 0.1156 | No |