Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classN
GeneSetSINGLE-ORGANISM MEMBRANE BUDDING
Enrichment Score (ES)0.4998282
Normalized Enrichment Score (NES)1.6781461
Nominal p-value0.014227643
FDR q-value1.0
FWER p-Value0.999
Table: GSEA Results Summary



Fig 1: Enrichment plot: SINGLE-ORGANISM MEMBRANE BUDDING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SEC24BSEC24B
Entrez,  Source
SEC24 related gene family, member B (S. cerevisiae)750.2410.0457Yes
2RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family3640.1890.0704Yes
3COPECOPE
Entrez,  Source
coatomer protein complex, subunit epsilon4510.1800.1029Yes
4CNIH3CNIH3
Entrez,  Source
cornichon homolog 3 (Drosophila)5300.1740.1347Yes
5F8F8
Entrez,  Source
coagulation factor VIII, procoagulant component (hemophilia A)6100.1690.1653Yes
6NAPANAPA
Entrez,  Source
N-ethylmaleimide-sensitive factor attachment protein, alpha11530.1400.1675Yes
7TRAPPC1TRAPPC1
Entrez,  Source
trafficking protein particle complex 115000.1270.1766Yes
8BET1BET1
Entrez,  Source
BET1 homolog (S. cerevisiae)16440.1230.1948Yes
9TMED2TMED2
Entrez,  Source
transmembrane emp24 domain trafficking protein 216600.1220.2190Yes
10CTSZCTSZ
Entrez,  Source
cathepsin Z19150.1140.2300Yes
11TRAPPC6BTRAPPC6B
Entrez,  Source
trafficking protein particle complex 6B20880.1090.2440Yes
12CD59CD59
Entrez,  Source
CD59 molecule, complement regulatory protein22000.1060.2603Yes
13SEC23IPSEC23IP
Entrez,  Source
SEC23 interacting protein22360.1050.2801Yes
14SEC22BSEC22B
Entrez,  Source
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)23530.1020.2954Yes
15MCFD2MCFD2
Entrez,  Source
multiple coagulation factor deficiency 223860.1020.3146Yes
16SEC23ASEC23A
Entrez,  Source
Sec23 homolog A (S. cerevisiae)25690.0970.3257Yes
17TRAPPC5TRAPPC5
Entrez,  Source
trafficking protein particle complex 525770.0970.3452Yes
18COPB2COPB2
Entrez,  Source
coatomer protein complex, subunit beta 2 (beta prime)26720.0950.3600Yes
19GOLPH3GOLPH3
Entrez,  Source
golgi phosphoprotein 3 (coat-protein)28100.0920.3721Yes
20F5F5
Entrez,  Source
coagulation factor V (proaccelerin, labile factor)29730.0880.3823Yes
21TGFATGFA
Entrez,  Source
transforming growth factor, alpha32590.0830.3853Yes
22SEC24DSEC24D
Entrez,  Source
SEC24 related gene family, member D (S. cerevisiae)32710.0820.4017Yes
23SEC24ASEC24A
Entrez,  Source
SEC24 related gene family, member A (S. cerevisiae)32730.0820.4185Yes
24TRAPPC3TRAPPC3
Entrez,  Source
trafficking protein particle complex 333260.0810.4325Yes
25SAR1BSAR1B
Entrez,  Source
SAR1 gene homolog B (S. cerevisiae)34370.0790.4434Yes
26SCFD1SCFD1
Entrez,  Source
sec1 family domain containing 135530.0770.4535Yes
27TRAPPC2TRAPPC2
Entrez,  Source
trafficking protein particle complex 236630.0750.4634Yes
28RILPRILP
Entrez,  Source
Rab interacting lysosomal protein37060.0740.4764Yes
29NSFNSF
Entrez,  Source
N-ethylmaleimide-sensitive factor37190.0730.4909Yes
30COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha38350.0710.4998Yes
31KLHL12KLHL12
Entrez,  Source
kelch-like 12 (Drosophila)42520.0630.4925No
32SERPINA1SERPINA1
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 152090.0480.4557No
33TMED9TMED9
Entrez,  Source
transmembrane emp24 protein transport domain containing 952530.0470.4633No
34TRAPPC6ATRAPPC6A
Entrez,  Source
trafficking protein particle complex 6A59050.0380.4394No
35CSNK1DCSNK1D
Entrez,  Source
casein kinase 1, delta60130.0360.4416No
36RAB1BRAB1B
Entrez,  Source
RAB1B, member RAS oncogene family61030.0350.4444No
37COPB1COPB1
Entrez,  Source
coatomer protein complex, subunit beta 169660.0240.4073No
38SNX3SNX3
Entrez,  Source
sorting nexin 371580.0210.4024No
39TFGTFG
Entrez,  Source
TRK-fused gene73920.0180.3948No
40TRAPPC2LTRAPPC2L
Entrez,  Source
trafficking protein particle complex 2-like77470.0140.3805No
41FOLR1FOLR1
Entrez,  Source
folate receptor 1 (adult)78560.0130.3778No
42VAPAVAPA
Entrez,  Source
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa81660.0080.3645No
43TRAPPC4TRAPPC4
Entrez,  Source
trafficking protein particle complex 481800.0080.3656No
44SEC31ASEC31A
Entrez,  Source
SEC31 homolog A (S. cerevisiae)86310.0030.3443No
45AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)87060.0020.3411No
46GOLGA2GOLGA2
Entrez,  Source
golgi autoantigen, golgin subfamily a, 29199-0.0040.3179No
47VAPBVAPB
Entrez,  Source
VAMP (vesicle-associated membrane protein)-associated protein B and C9204-0.0040.3184No
48ARF1ARF1
Entrez,  Source
ADP-ribosylation factor 19245-0.0040.3173No
49TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)9658-0.0090.2990No
50PPP6CPPP6C
Entrez,  Source
protein phosphatase 6, catalytic subunit9978-0.0120.2860No
51LMAN1LMAN1
Entrez,  Source
lectin, mannose-binding, 110286-0.0150.2742No
52ANKRD28ANKRD28
Entrez,  Source
ankyrin repeat domain 2810295-0.0160.2770No
53ARCN1ARCN1
Entrez,  Source
archain 110472-0.0180.2720No
54CUL3CUL3
Entrez,  Source
cullin 310774-0.0210.2617No
55GORASP1GORASP1
Entrez,  Source
golgi reassembly stacking protein 1, 65kDa11260-0.0260.2435No
56GBF1GBF1
Entrez,  Source
golgi-specific brefeldin A resistance factor 111953-0.0340.2168No
57CNIH2CNIH2
Entrez,  Source
cornichon homolog 2 (Drosophila)12922-0.0450.1789No
58COPZ1COPZ1
Entrez,  Source
coatomer protein complex, subunit zeta 113522-0.0510.1602No
59TBC1D20TBC1D20
Entrez,  Source
TBC1 domain family, member 2014663-0.0650.1180No
60CTSCCTSC
Entrez,  Source
cathepsin C15317-0.0730.1011No
61COL7A1COL7A1
Entrez,  Source
collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive)15720-0.0780.0975No
62GOSR2GOSR2
Entrez,  Source
golgi SNAP receptor complex member 216666-0.0920.0704No
63GRIA1GRIA1
Entrez,  Source
glutamate receptor, ionotropic, AMPA 116920-0.0960.0777No
64SEC24CSEC24C
Entrez,  Source
SEC24 related gene family, member C (S. cerevisiae)17684-0.1080.0627No
65PREBPREB
Entrez,  Source
prolactin regulatory element binding17766-0.1100.0812No
66STX5STX5
Entrez,  Source
syntaxin 518695-0.1290.0624No
67ARFGAP1ARFGAP1
Entrez,  Source
ADP-ribosylation factor GTPase activating protein 119414-0.1490.0580No
Table: GSEA details [plain text format]



Fig 2: SINGLE-ORGANISM MEMBRANE BUDDING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: SINGLE-ORGANISM MEMBRANE BUDDING: Random ES distribution   
Gene set null distribution of ES for SINGLE-ORGANISM MEMBRANE BUDDING