Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classN
GeneSetVESICLE TARGETING, TO, FROM OR WITHIN GOLGI
Enrichment Score (ES)0.50974447
Normalized Enrichment Score (NES)1.6916429
Nominal p-value0.004008016
FDR q-value1.0
FWER p-Value0.999
Table: GSEA Results Summary



Fig 1: Enrichment plot: VESICLE TARGETING, TO, FROM OR WITHIN GOLGI   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SEC24BSEC24B
Entrez,  Source
SEC24 related gene family, member B (S. cerevisiae)750.2410.0474Yes
2RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family3640.1890.0734Yes
3COPECOPE
Entrez,  Source
coatomer protein complex, subunit epsilon4510.1800.1072Yes
4CNIH3CNIH3
Entrez,  Source
cornichon homolog 3 (Drosophila)5300.1740.1402Yes
5F8F8
Entrez,  Source
coagulation factor VIII, procoagulant component (hemophilia A)6100.1690.1721Yes
6NAPANAPA
Entrez,  Source
N-ethylmaleimide-sensitive factor attachment protein, alpha11530.1400.1752Yes
7TRAPPC1TRAPPC1
Entrez,  Source
trafficking protein particle complex 115000.1270.1853Yes
8BET1BET1
Entrez,  Source
BET1 homolog (S. cerevisiae)16440.1230.2042Yes
9TMED2TMED2
Entrez,  Source
transmembrane emp24 domain trafficking protein 216600.1220.2294Yes
10CTSZCTSZ
Entrez,  Source
cathepsin Z19150.1140.2411Yes
11TRAPPC6BTRAPPC6B
Entrez,  Source
trafficking protein particle complex 6B20880.1090.2559Yes
12CD59CD59
Entrez,  Source
CD59 molecule, complement regulatory protein22000.1060.2730Yes
13SEC23IPSEC23IP
Entrez,  Source
SEC23 interacting protein22360.1050.2935Yes
14SEC22BSEC22B
Entrez,  Source
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)23530.1020.3096Yes
15MCFD2MCFD2
Entrez,  Source
multiple coagulation factor deficiency 223860.1020.3295Yes
16WIPI1WIPI1
Entrez,  Source
WD repeat domain, phosphoinositide interacting 124310.1000.3486Yes
17SEC23ASEC23A
Entrez,  Source
Sec23 homolog A (S. cerevisiae)25690.0970.3625Yes
18TRAPPC5TRAPPC5
Entrez,  Source
trafficking protein particle complex 525770.0970.3828Yes
19COPB2COPB2
Entrez,  Source
coatomer protein complex, subunit beta 2 (beta prime)26720.0950.3983Yes
20F5F5
Entrez,  Source
coagulation factor V (proaccelerin, labile factor)29730.0880.4024Yes
21TGFATGFA
Entrez,  Source
transforming growth factor, alpha32590.0830.4060Yes
22SEC24DSEC24D
Entrez,  Source
SEC24 related gene family, member D (S. cerevisiae)32710.0820.4229Yes
23SEC24ASEC24A
Entrez,  Source
SEC24 related gene family, member A (S. cerevisiae)32730.0820.4403Yes
24TRAPPC3TRAPPC3
Entrez,  Source
trafficking protein particle complex 333260.0810.4549Yes
25SAR1BSAR1B
Entrez,  Source
SAR1 gene homolog B (S. cerevisiae)34370.0790.4663Yes
26SCFD1SCFD1
Entrez,  Source
sec1 family domain containing 135530.0770.4770Yes
27TRAPPC2TRAPPC2
Entrez,  Source
trafficking protein particle complex 236630.0750.4874Yes
28NSFNSF
Entrez,  Source
N-ethylmaleimide-sensitive factor37190.0730.5003Yes
29COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha38350.0710.5097Yes
30KLHL12KLHL12
Entrez,  Source
kelch-like 12 (Drosophila)42520.0630.5028No
31SERPINA1SERPINA1
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 152090.0480.4665No
32TMED9TMED9
Entrez,  Source
transmembrane emp24 protein transport domain containing 952530.0470.4744No
33TRAPPC6ATRAPPC6A
Entrez,  Source
trafficking protein particle complex 6A59050.0380.4507No
34CSNK1DCSNK1D
Entrez,  Source
casein kinase 1, delta60130.0360.4532No
35RAB1BRAB1B
Entrez,  Source
RAB1B, member RAS oncogene family61030.0350.4563No
36COPB1COPB1
Entrez,  Source
coatomer protein complex, subunit beta 169660.0240.4193No
37TFGTFG
Entrez,  Source
TRK-fused gene73920.0180.4026No
38TRAPPC2LTRAPPC2L
Entrez,  Source
trafficking protein particle complex 2-like77470.0140.3883No
39FOLR1FOLR1
Entrez,  Source
folate receptor 1 (adult)78560.0130.3857No
40TRAPPC4TRAPPC4
Entrez,  Source
trafficking protein particle complex 481800.0080.3718No
41SEC31ASEC31A
Entrez,  Source
SEC31 homolog A (S. cerevisiae)86310.0030.3505No
42AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)87060.0020.3473No
43GOLGA2GOLGA2
Entrez,  Source
golgi autoantigen, golgin subfamily a, 29199-0.0040.3241No
44ARF1ARF1
Entrez,  Source
ADP-ribosylation factor 19245-0.0040.3228No
45TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)9658-0.0090.3046No
46PPP6CPPP6C
Entrez,  Source
protein phosphatase 6, catalytic subunit9978-0.0120.2916No
47LMAN1LMAN1
Entrez,  Source
lectin, mannose-binding, 110286-0.0150.2799No
48ANKRD28ANKRD28
Entrez,  Source
ankyrin repeat domain 2810295-0.0160.2829No
49ARCN1ARCN1
Entrez,  Source
archain 110472-0.0180.2780No
50CUL3CUL3
Entrez,  Source
cullin 310774-0.0210.2679No
51GORASP1GORASP1
Entrez,  Source
golgi reassembly stacking protein 1, 65kDa11260-0.0260.2498No
52GBF1GBF1
Entrez,  Source
golgi-specific brefeldin A resistance factor 111953-0.0340.2234No
53CNIH2CNIH2
Entrez,  Source
cornichon homolog 2 (Drosophila)12922-0.0450.1858No
54COPZ1COPZ1
Entrez,  Source
coatomer protein complex, subunit zeta 113522-0.0510.1675No
55CTSCCTSC
Entrez,  Source
cathepsin C15317-0.0730.0956No
56COL7A1COL7A1
Entrez,  Source
collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive)15720-0.0780.0926No
57GOSR2GOSR2
Entrez,  Source
golgi SNAP receptor complex member 216666-0.0920.0662No
58GRIA1GRIA1
Entrez,  Source
glutamate receptor, ionotropic, AMPA 116920-0.0960.0741No
59SEC24CSEC24C
Entrez,  Source
SEC24 related gene family, member C (S. cerevisiae)17684-0.1080.0599No
60PREBPREB
Entrez,  Source
prolactin regulatory element binding17766-0.1100.0792No
61STX5STX5
Entrez,  Source
syntaxin 518695-0.1290.0613No
62ARFGAP1ARFGAP1
Entrez,  Source
ADP-ribosylation factor GTPase activating protein 119414-0.1490.0580No
Table: GSEA details [plain text format]



Fig 2: VESICLE TARGETING, TO, FROM OR WITHIN GOLGI   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VESICLE TARGETING, TO, FROM OR WITHIN GOLGI: Random ES distribution   
Gene set null distribution of ES for VESICLE TARGETING, TO, FROM OR WITHIN GOLGI