Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classN
GeneSetANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I, TAP-DEPENDENT
Enrichment Score (ES)0.5547463
Normalized Enrichment Score (NES)1.6959057
Nominal p-value0.0373444
FDR q-value1.0
FWER p-Value0.999
Table: GSEA Results Summary



Fig 1: Enrichment plot: ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I, TAP-DEPENDENT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)970.2300.0434Yes
2PSMB9PSMB9
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)2940.1970.0749Yes
3CYBACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide5220.1750.1003Yes
4CD36CD36
Entrez,  Source
CD36 molecule (thrombospondin receptor)5430.1730.1354Yes
5FCGR1AFCGR1A
Entrez,  Source
Fc fragment of IgG, high affinity Ia, receptor (CD64)7190.1600.1604Yes
6PDIA3PDIA3
Entrez,  Source
protein disulfide isomerase family A, member 39630.1480.1795Yes
7SEC61GSEC61G
Entrez,  Source
Sec61 gamma subunit12830.1340.1920Yes
8PSMC6PSMC6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 612880.1340.2198Yes
9SEC61A2SEC61A2
Entrez,  Source
Sec61 alpha 2 subunit (S. cerevisiae)13660.1310.2435Yes
10PSMA3PSMA3
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 314130.1300.2683Yes
11PSMD12PSMD12
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1215100.1270.2901Yes
12NCF4NCF4
Entrez,  Source
neutrophil cytosolic factor 4, 40kDa16360.1230.3096Yes
13PSMD10PSMD10
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1017600.1190.3285Yes
14ITGAVITGAV
Entrez,  Source
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)18420.1160.3488Yes
15PSMB2PSMB2
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 221390.1080.3569Yes
16PSMA4PSMA4
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 425110.0990.3594Yes
17PSMB10PSMB10
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 1026490.0950.3727Yes
18NCF2NCF2
Entrez,  Source
neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)27730.0930.3860Yes
19PSMB8PSMB8
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)29210.0890.3975Yes
20SEC61BSEC61B
Entrez,  Source
Sec61 beta subunit30230.0870.4108Yes
21PSMD5PSMD5
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 530300.0870.4287Yes
22PSMA2PSMA2
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 230890.0860.4437Yes
23PSMB3PSMB3
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 331050.0850.4608Yes
24TAP2TAP2
Entrez,  Source
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)32960.0820.4687Yes
25TAP1TAP1
Entrez,  Source
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)33890.0800.4809Yes
26UBCUBC
Entrez,  Source
ubiquitin C36720.0740.4827Yes
27PSMB7PSMB7
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 738720.0710.4877Yes
28PSMF1PSMF1
Entrez,  Source
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)40260.0670.4943Yes
29HLA-EHLA-E
Entrez,  Source
major histocompatibility complex, class I, E40760.0660.5058Yes
30PSMD14PSMD14
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1446150.0570.4916Yes
31PSME1PSME1
Entrez,  Source
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)46710.0560.5007Yes
32HLA-FHLA-F
Entrez,  Source
major histocompatibility complex, class I, F46980.0560.5111Yes
33PSMD9PSMD9
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 948080.0540.5171Yes
34PSMD7PSMD7
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)51830.0480.5091Yes
35PSMD13PSMD13
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1352360.0480.5165Yes
36PSMB6PSMB6
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 654210.0450.5168Yes
37PSMD3PSMD3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 355490.0430.5195Yes
38PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 456060.0420.5255Yes
39HLA-AHLA-A
Entrez,  Source
major histocompatibility complex, class I, A56260.0420.5333Yes
40PSMA5PSMA5
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 557230.0400.5370Yes
41HLA-GHLA-G
Entrez,  Source
HLA-G histocompatibility antigen, class I, G57810.0390.5424Yes
42PSMD8PSMD8
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 858240.0390.5485Yes
43PSME2PSME2
Entrez,  Source
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)58610.0380.5547Yes
44PSMD6PSMD6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 663280.0320.5388No
45PSMA7PSMA7
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 765450.0290.5344No
46PSME3PSME3
Entrez,  Source
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)66660.0280.5344No
47PSMB4PSMB4
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 473620.0190.5045No
48PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 673690.0190.5081No
49PSMC1PSMC1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 174250.0180.5092No
50PSMA8PSMA8
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 875940.0160.5043No
51CALRCALR
Entrez,  Source
calreticulin75970.0160.5075No
52PSMD2PSMD2
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 277240.0140.5043No
53PSMC2PSMC2
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 277680.0140.5051No
54PSMD4PSMD4
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 478480.0130.5039No
55HLA-CHLA-C
Entrez,  Source
major histocompatibility complex, class I, C81600.0090.4906No
56PSMB1PSMB1
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 184590.0050.4771No
57PSMD11PSMD11
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1186110.0030.4704No
58HLA-BHLA-B
Entrez,  Source
major histocompatibility complex, class I, B87310.0020.4650No
59UBA52UBA52
Entrez,  Source
ubiquitin A-52 residue ribosomal protein fusion product 18957-0.0010.4542No
60TAPBPTAPBP
Entrez,  Source
TAP binding protein (tapasin)9030-0.0020.4511No
61PSMA1PSMA1
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 19405-0.0060.4341No
62B2MB2M
Entrez,  Source
beta-2-microglobulin9578-0.0080.4273No
63PSMB5PSMB5
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 59941-0.0120.4121No
64UBBUBB
Entrez,  Source
ubiquitin B11292-0.0270.3520No
65PSMC3PSMC3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 311720-0.0320.3378No
66PSMD1PSMD1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 113035-0.0460.2835No
67PSMC5PSMC5
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 513791-0.0540.2580No
68RPS27ARPS27A
Entrez,  Source
ribosomal protein S27a14405-0.0620.2410No
69SEC61A1SEC61A1
Entrez,  Source
Sec61 alpha 1 subunit (S. cerevisiae)15029-0.0690.2252No
70ITGB5ITGB5
Entrez,  Source
integrin, beta 517272-0.1010.1372No
71CD207CD207
Entrez,  Source
CD207 molecule, langerin18298-0.1200.1123No
Table: GSEA details [plain text format]



Fig 2: ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I, TAP-DEPENDENT   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I, TAP-DEPENDENT: Random ES distribution   
Gene set null distribution of ES for ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I, TAP-DEPENDENT