Dataset | gse25507_collapsed_to_symbols.gse25507.gpl570.cls #N_versus_Y.gse25507.gpl570.cls #N_versus_Y_repos |
Phenotype | gse25507.gpl570.cls#N_versus_Y_repos |
Upregulated in class | Y |
GeneSet | REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS |
Enrichment Score (ES) | -0.5394308 |
Normalized Enrichment Score (NES) | -1.8359708 |
Nominal p-value | 0.003984064 |
FDR q-value | 0.544343 |
FWER p-Value | 0.85 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | GSK3B | GSK3B Entrez,  Source | glycogen synthase kinase 3 beta | 2812 | 0.092 | -0.1065 | No |
2 | FBP1 | FBP1 Entrez,  Source | fructose-1,6-bisphosphatase 1 | 3379 | 0.080 | -0.1075 | No |
3 | AP2A1 | AP2A1 Entrez,  Source | adaptor-related protein complex 2, alpha 1 subunit | 4269 | 0.063 | -0.1300 | No |
4 | AKT1 | AKT1 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 1 | 4843 | 0.054 | -0.1402 | No |
5 | CLTC | CLTC Entrez,  Source | clathrin, heavy chain (Hc) | 5111 | 0.050 | -0.1368 | No |
6 | IRS1 | IRS1 Entrez,  Source | insulin receptor substrate 1 | 6397 | 0.031 | -0.1889 | No |
7 | PDK2 | PDK2 Entrez,  Source | pyruvate dehydrogenase kinase, isozyme 2 | 6503 | 0.030 | -0.1842 | No |
8 | SORBS1 | SORBS1 Entrez,  Source | sorbin and SH3 domain containing 1 | 7232 | 0.020 | -0.2129 | No |
9 | NFKB1 | NFKB1 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7558 | 0.016 | -0.2233 | No |
10 | TGFB1 | TGFB1 Entrez,  Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 7867 | 0.012 | -0.2342 | No |
11 | PLEK | PLEK Entrez,  Source | pleckstrin | 8825 | 0.001 | -0.2805 | No |
12 | AKT2 | AKT2 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 2 | 8973 | -0.001 | -0.2873 | No |
13 | GRB10 | GRB10 Entrez,  Source | growth factor receptor-bound protein 10 | 10345 | -0.016 | -0.3486 | No |
14 | ADIPOQ | ADIPOQ Entrez,  Source | adiponectin, C1Q and collagen domain containing | 10560 | -0.019 | -0.3529 | No |
15 | IGF2 | IGF2 Entrez,  Source | insulin-like growth factor 2 (somatomedin A) | 10962 | -0.023 | -0.3647 | No |
16 | IRS2 | IRS2 Entrez,  Source | insulin receptor substrate 2 | 11294 | -0.027 | -0.3720 | No |
17 | C1QTNF3 | C1QTNF3 Entrez,  Source | C1q and tumor necrosis factor related protein 3 | 11347 | -0.027 | -0.3655 | No |
18 | PPP1R3F | PPP1R3F Entrez,  Source | protein phosphatase 1, regulatory (inhibitor) subunit 3F | 12394 | -0.039 | -0.4035 | No |
19 | PTPN2 | PTPN2 Entrez,  Source | protein tyrosine phosphatase, non-receptor type 2 | 12614 | -0.041 | -0.4005 | No |
20 | HRH1 | HRH1 Entrez,  Source | histamine receptor H1 | 12906 | -0.045 | -0.3998 | No |
21 | PTH | PTH Entrez,  Source | parathyroid hormone | 13052 | -0.046 | -0.3916 | No |
22 | PDGFB | PDGFB Entrez,  Source | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 14957 | -0.068 | -0.4616 | No |
23 | INSR | INSR Entrez,  Source | insulin receptor | 16558 | -0.090 | -0.5097 | Yes |
24 | PTK2B | PTK2B Entrez,  Source | PTK2B protein tyrosine kinase 2 beta | 16560 | -0.090 | -0.4800 | Yes |
25 | DYRK2 | DYRK2 Entrez,  Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 16562 | -0.090 | -0.4503 | Yes |
26 | LHCGR | LHCGR Entrez,  Source | luteinizing hormone/choriogonadotropin receptor | 16890 | -0.095 | -0.4347 | Yes |
27 | PPARGC1A | PPARGC1A Entrez,  Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 16917 | -0.096 | -0.4044 | Yes |
28 | ENPP1 | ENPP1 Entrez,  Source | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 17669 | -0.108 | -0.4053 | Yes |
29 | EGF | EGF Entrez,  Source | epidermal growth factor (beta-urogastrone) | 17673 | -0.108 | -0.3698 | Yes |
30 | GSK3A | GSK3A Entrez,  Source | glycogen synthase kinase 3 alpha | 17985 | -0.114 | -0.3474 | Yes |
31 | OGT | OGT Entrez,  Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 18349 | -0.121 | -0.3250 | Yes |
32 | IGF1 | IGF1 Entrez,  Source | insulin-like growth factor 1 (somatomedin C) | 18861 | -0.133 | -0.3060 | Yes |
33 | GCK | GCK Entrez,  Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 19436 | -0.150 | -0.2843 | Yes |
34 | INS | INS Entrez,  Source | insulin | 19627 | -0.158 | -0.2414 | Yes |
35 | PASK | PASK Entrez,  Source | PAS domain containing serine/threonine kinase | 19746 | -0.163 | -0.1933 | Yes |
36 | CLK2 | CLK2 Entrez,  Source | CDC-like kinase 2 | 19828 | -0.167 | -0.1421 | Yes |
37 | SNCA | SNCA Entrez,  Source | synuclein, alpha (non A4 component of amyloid precursor) | 20447 | -0.227 | -0.0973 | Yes |
38 | CD244 | CD244 Entrez,  Source | CD244 molecule, natural killer cell receptor 2B4 | 20602 | -0.318 | 0.0001 | Yes |