Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classY
GeneSetREGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS
Enrichment Score (ES)-0.5394308
Normalized Enrichment Score (NES)-1.8359708
Nominal p-value0.003984064
FDR q-value0.544343
FWER p-Value0.85
Table: GSEA Results Summary



Fig 1: Enrichment plot: REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta28120.092-0.1065No
2FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 133790.080-0.1075No
3AP2A1AP2A1
Entrez,  Source
adaptor-related protein complex 2, alpha 1 subunit42690.063-0.1300No
4AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 148430.054-0.1402No
5CLTCCLTC
Entrez,  Source
clathrin, heavy chain (Hc)51110.050-0.1368No
6IRS1IRS1
Entrez,  Source
insulin receptor substrate 163970.031-0.1889No
7PDK2PDK2
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 265030.030-0.1842No
8SORBS1SORBS1
Entrez,  Source
sorbin and SH3 domain containing 172320.020-0.2129No
9NFKB1NFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)75580.016-0.2233No
10TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)78670.012-0.2342No
11PLEKPLEK
Entrez,  Source
pleckstrin88250.001-0.2805No
12AKT2AKT2
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 28973-0.001-0.2873No
13GRB10GRB10
Entrez,  Source
growth factor receptor-bound protein 1010345-0.016-0.3486No
14ADIPOQADIPOQ
Entrez,  Source
adiponectin, C1Q and collagen domain containing10560-0.019-0.3529No
15IGF2IGF2
Entrez,  Source
insulin-like growth factor 2 (somatomedin A)10962-0.023-0.3647No
16IRS2IRS2
Entrez,  Source
insulin receptor substrate 211294-0.027-0.3720No
17C1QTNF3C1QTNF3
Entrez,  Source
C1q and tumor necrosis factor related protein 311347-0.027-0.3655No
18PPP1R3FPPP1R3F
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 3F12394-0.039-0.4035No
19PTPN2PTPN2
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 212614-0.041-0.4005No
20HRH1HRH1
Entrez,  Source
histamine receptor H112906-0.045-0.3998No
21PTHPTH
Entrez,  Source
parathyroid hormone13052-0.046-0.3916No
22PDGFBPDGFB
Entrez,  Source
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)14957-0.068-0.4616No
23INSRINSR
Entrez,  Source
insulin receptor16558-0.090-0.5097Yes
24PTK2BPTK2B
Entrez,  Source
PTK2B protein tyrosine kinase 2 beta16560-0.090-0.4800Yes
25DYRK2DYRK2
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 216562-0.090-0.4503Yes
26LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor16890-0.095-0.4347Yes
27PPARGC1APPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha16917-0.096-0.4044Yes
28ENPP1ENPP1
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 117669-0.108-0.4053Yes
29EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)17673-0.108-0.3698Yes
30GSK3AGSK3A
Entrez,  Source
glycogen synthase kinase 3 alpha17985-0.114-0.3474Yes
31OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)18349-0.121-0.3250Yes
32IGF1IGF1
Entrez,  Source
insulin-like growth factor 1 (somatomedin C)18861-0.133-0.3060Yes
33GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)19436-0.150-0.2843Yes
34INSINS
Entrez,  Source
insulin19627-0.158-0.2414Yes
35PASKPASK
Entrez,  Source
PAS domain containing serine/threonine kinase19746-0.163-0.1933Yes
36CLK2CLK2
Entrez,  Source
CDC-like kinase 219828-0.167-0.1421Yes
37SNCASNCA
Entrez,  Source
synuclein, alpha (non A4 component of amyloid precursor)20447-0.227-0.0973Yes
38CD244CD244
Entrez,  Source
CD244 molecule, natural killer cell receptor 2B420602-0.3180.0001Yes
Table: GSEA details [plain text format]



Fig 2: REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS: Random ES distribution   
Gene set null distribution of ES for REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS