Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classN
GeneSetLOCALIZATION WITHIN MEMBRANE
Enrichment Score (ES)0.48220327
Normalized Enrichment Score (NES)1.6957306
Nominal p-value0.00591716
FDR q-value1.0
FWER p-Value0.999
Table: GSEA Results Summary



Fig 1: Enrichment plot: LOCALIZATION WITHIN MEMBRANE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SEC24BSEC24B
Entrez,  Source
SEC24 related gene family, member B (S. cerevisiae)750.2410.0439Yes
2RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family3640.1890.0672Yes
3COPECOPE
Entrez,  Source
coatomer protein complex, subunit epsilon4510.1800.0984Yes
4CNIH3CNIH3
Entrez,  Source
cornichon homolog 3 (Drosophila)5300.1740.1289Yes
5F8F8
Entrez,  Source
coagulation factor VIII, procoagulant component (hemophilia A)6100.1690.1583Yes
6NAPANAPA
Entrez,  Source
N-ethylmaleimide-sensitive factor attachment protein, alpha11530.1400.1594Yes
7TRAPPC1TRAPPC1
Entrez,  Source
trafficking protein particle complex 115000.1270.1676Yes
8BET1BET1
Entrez,  Source
BET1 homolog (S. cerevisiae)16440.1230.1849Yes
9TMED2TMED2
Entrez,  Source
transmembrane emp24 domain trafficking protein 216600.1220.2082Yes
10CTSZCTSZ
Entrez,  Source
cathepsin Z19150.1140.2184Yes
11TRAPPC6BTRAPPC6B
Entrez,  Source
trafficking protein particle complex 6B20880.1090.2315Yes
12CD59CD59
Entrez,  Source
CD59 molecule, complement regulatory protein22000.1060.2471Yes
13SEC23IPSEC23IP
Entrez,  Source
SEC23 interacting protein22360.1050.2661Yes
14SEC22BSEC22B
Entrez,  Source
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)23530.1020.2807Yes
15MCFD2MCFD2
Entrez,  Source
multiple coagulation factor deficiency 223860.1020.2991Yes
16SEC23ASEC23A
Entrez,  Source
Sec23 homolog A (S. cerevisiae)25690.0970.3095Yes
17TRAPPC5TRAPPC5
Entrez,  Source
trafficking protein particle complex 525770.0970.3283Yes
18COPB2COPB2
Entrez,  Source
coatomer protein complex, subunit beta 2 (beta prime)26720.0950.3424Yes
19GOLPH3GOLPH3
Entrez,  Source
golgi phosphoprotein 3 (coat-protein)28100.0920.3538Yes
20F5F5
Entrez,  Source
coagulation factor V (proaccelerin, labile factor)29730.0880.3634Yes
21TGFATGFA
Entrez,  Source
transforming growth factor, alpha32590.0830.3658Yes
22SEC24DSEC24D
Entrez,  Source
SEC24 related gene family, member D (S. cerevisiae)32710.0820.3815Yes
23SEC24ASEC24A
Entrez,  Source
SEC24 related gene family, member A (S. cerevisiae)32730.0820.3977Yes
24TRAPPC3TRAPPC3
Entrez,  Source
trafficking protein particle complex 333260.0810.4112Yes
25SAR1BSAR1B
Entrez,  Source
SAR1 gene homolog B (S. cerevisiae)34370.0790.4214Yes
26SCFD1SCFD1
Entrez,  Source
sec1 family domain containing 135530.0770.4310Yes
27TRAPPC2TRAPPC2
Entrez,  Source
trafficking protein particle complex 236630.0750.4403Yes
28RILPRILP
Entrez,  Source
Rab interacting lysosomal protein37060.0740.4528Yes
29NSFNSF
Entrez,  Source
N-ethylmaleimide-sensitive factor37190.0730.4667Yes
30COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha38350.0710.4752Yes
31RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)39680.0680.4822Yes
32KLHL12KLHL12
Entrez,  Source
kelch-like 12 (Drosophila)42520.0630.4809No
33SERPINA1SERPINA1
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 152090.0480.4438No
34TMED9TMED9
Entrez,  Source
transmembrane emp24 protein transport domain containing 952530.0470.4510No
35CDH13CDH13
Entrez,  Source
cadherin 13, H-cadherin (heart)57990.0390.4322No
36TRAPPC6ATRAPPC6A
Entrez,  Source
trafficking protein particle complex 6A59050.0380.4345No
37CSNK1DCSNK1D
Entrez,  Source
casein kinase 1, delta60130.0360.4365No
38RAB1BRAB1B
Entrez,  Source
RAB1B, member RAS oncogene family61030.0350.4391No
39COPB1COPB1
Entrez,  Source
coatomer protein complex, subunit beta 169660.0240.4018No
40SNX3SNX3
Entrez,  Source
sorting nexin 371580.0210.3967No
41TFGTFG
Entrez,  Source
TRK-fused gene73920.0180.3890No
42TRAPPC2LTRAPPC2L
Entrez,  Source
trafficking protein particle complex 2-like77470.0140.3745No
43FOLR1FOLR1
Entrez,  Source
folate receptor 1 (adult)78560.0130.3718No
44VAPAVAPA
Entrez,  Source
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa81660.0080.3584No
45TRAPPC4TRAPPC4
Entrez,  Source
trafficking protein particle complex 481800.0080.3594No
46CD2CD2
Entrez,  Source
CD2 molecule84080.0060.3495No
47SEC31ASEC31A
Entrez,  Source
SEC31 homolog A (S. cerevisiae)86310.0030.3392No
48AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)87060.0020.3360No
49GOLGA2GOLGA2
Entrez,  Source
golgi autoantigen, golgin subfamily a, 29199-0.0040.3128No
50VAPBVAPB
Entrez,  Source
VAMP (vesicle-associated membrane protein)-associated protein B and C9204-0.0040.3133No
51ARF1ARF1
Entrez,  Source
ADP-ribosylation factor 19245-0.0040.3122No
52RALARALA
Entrez,  Source
v-ral simian leukemia viral oncogene homolog A (ras related)9562-0.0070.2983No
53TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)9658-0.0090.2953No
54PPP6CPPP6C
Entrez,  Source
protein phosphatase 6, catalytic subunit9978-0.0120.2822No
55LMAN1LMAN1
Entrez,  Source
lectin, mannose-binding, 110286-0.0150.2703No
56ANKRD28ANKRD28
Entrez,  Source
ankyrin repeat domain 2810295-0.0160.2729No
57ARCN1ARCN1
Entrez,  Source
archain 110472-0.0180.2678No
58CUL3CUL3
Entrez,  Source
cullin 310774-0.0210.2574No
59GORASP1GORASP1
Entrez,  Source
golgi reassembly stacking protein 1, 65kDa11260-0.0260.2390No
60GBF1GBF1
Entrez,  Source
golgi-specific brefeldin A resistance factor 111953-0.0340.2121No
61CNIH2CNIH2
Entrez,  Source
cornichon homolog 2 (Drosophila)12922-0.0450.1738No
62COPZ1COPZ1
Entrez,  Source
coatomer protein complex, subunit zeta 113522-0.0510.1547No
63MALMAL
Entrez,  Source
mal, T-cell differentiation protein14409-0.0620.1238No
64TBC1D20TBC1D20
Entrez,  Source
TBC1 domain family, member 2014663-0.0650.1242No
65CTSCCTSC
Entrez,  Source
cathepsin C15317-0.0730.1067No
66COL7A1COL7A1
Entrez,  Source
collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive)15720-0.0780.1026No
67GOSR2GOSR2
Entrez,  Source
golgi SNAP receptor complex member 216666-0.0920.0748No
68GRIA1GRIA1
Entrez,  Source
glutamate receptor, ionotropic, AMPA 116920-0.0960.0814No
69SEC24CSEC24C
Entrez,  Source
SEC24 related gene family, member C (S. cerevisiae)17684-0.1080.0656No
70PREBPREB
Entrez,  Source
prolactin regulatory element binding17766-0.1100.0833No
71STX5STX5
Entrez,  Source
syntaxin 518695-0.1290.0635No
72ARFGAP1ARFGAP1
Entrez,  Source
ADP-ribosylation factor GTPase activating protein 119414-0.1490.0580No
Table: GSEA details [plain text format]



Fig 2: LOCALIZATION WITHIN MEMBRANE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: LOCALIZATION WITHIN MEMBRANE: Random ES distribution   
Gene set null distribution of ES for LOCALIZATION WITHIN MEMBRANE