Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classY
GeneSetPHOTOTRANSDUCTION
Enrichment Score (ES)-0.4675881
Normalized Enrichment Score (NES)-1.7922312
Nominal p-value0.003960396
FDR q-value0.4666552
FWER p-Value0.943
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHOTOTRANSDUCTION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PLB1PLB1
Entrez,  Source
phospholipase B125920.097-0.1114No
2METAP2METAP2
Entrez,  Source
methionyl aminopeptidase 228030.092-0.1074No
3APOMAPOM
Entrez,  Source
apolipoprotein M31230.085-0.1098No
4RBP3RBP3
Entrez,  Source
retinol binding protein 3, interstitial35040.078-0.1163No
5SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)41060.066-0.1354No
6AKR1C4AKR1C4
Entrez,  Source
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)41410.065-0.1269No
7RDH10RDH10
Entrez,  Source
retinol dehydrogenase 10 (all-trans)42000.064-0.1198No
8LRP8LRP8
Entrez,  Source
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor42300.063-0.1114No
9LRP1LRP1
Entrez,  Source
low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)46810.056-0.1247No
10CYP4V2CYP4V2
Entrez,  Source
cytochrome P450, family 4, subfamily V, polypeptide 253170.046-0.1484No
11PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha53950.045-0.1452No
12FNTBFNTB
Entrez,  Source
farnesyltransferase, CAAX box, beta55520.043-0.1462No
13GUCA1BGUCA1B
Entrez,  Source
guanylate cyclase activator 1B (retina)56820.041-0.1462No
14GUCY2DGUCY2D
Entrez,  Source
guanylate cyclase 2D, membrane (retina-specific)63810.032-0.1754No
15TRPC3TRPC3
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 364250.031-0.1727No
16UNC119UNC119
Entrez,  Source
unc-119 homolog (C. elegans)67870.026-0.1862No
17GRK4GRK4
Entrez,  Source
G protein-coupled receptor kinase 473870.019-0.2125No
18SLC24A1SLC24A1
Entrez,  Source
solute carrier family 24 (sodium/potassium/calcium exchanger), member 177750.014-0.2293No
19NMT2NMT2
Entrez,  Source
N-myristoyltransferase 278860.012-0.2328No
20RDH8RDH8
Entrez,  Source
retinol dehydrogenase 8 (all-trans)80370.010-0.2385No
21SDC4SDC4
Entrez,  Source
syndecan 4 (amphiglycan, ryudocan)82190.008-0.2461No
22GNB1GNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 185620.004-0.2622No
23LRATLRAT
Entrez,  Source
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)85900.003-0.2630No
24FNTAFNTA
Entrez,  Source
farnesyltransferase, CAAX box, alpha86190.003-0.2639No
25GNA11GNA11
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)86730.002-0.2661No
26SDC3SDC3
Entrez,  Source
syndecan 3 (N-syndecan)8922-0.000-0.2781No
27STRA6STRA6
Entrez,  Source
stimulated by retinoic acid gene 6 homolog (mouse)8962-0.001-0.2799No
28SAGSAG
Entrez,  Source
S-antigen; retina and pineal gland (arrestin)9054-0.002-0.2840No
29PNLIPPNLIP
Entrez,  Source
pancreatic lipase9365-0.005-0.2982No
30GPC5GPC5
Entrez,  Source
glypican 59471-0.007-0.3023No
31LDLRLDLR
Entrez,  Source
low density lipoprotein receptor (familial hypercholesterolemia)9530-0.007-0.3041No
32RGS9BPRGS9BP
Entrez,  Source
regulator of G protein signalling 9 binding protein9550-0.007-0.3038No
33RLBP1RLBP1
Entrez,  Source
retinaldehyde binding protein 19868-0.011-0.3176No
34GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide9931-0.011-0.3189No
35RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma9987-0.012-0.3197No
36RP1RP1
Entrez,  Source
retinitis pigmentosa 1 (autosomal dominant)10285-0.015-0.3318No
37CNGA1CNGA1
Entrez,  Source
cyclic nucleotide gated channel alpha 110447-0.017-0.3369No
38NMT1NMT1
Entrez,  Source
N-myristoyltransferase 110563-0.019-0.3397No
39CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)10628-0.019-0.3398No
40RDH11RDH11
Entrez,  Source
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)10643-0.020-0.3374No
41SDC1SDC1
Entrez,  Source
syndecan 111322-0.027-0.3662No
42OPN4OPN4
Entrez,  Source
opsin 4 (melanopsin)11597-0.031-0.3749No
43APOEAPOE
Entrez,  Source
apolipoprotein E11705-0.032-0.3752No
44GNB5GNB5
Entrez,  Source
guanine nucleotide binding protein (G protein), beta 512657-0.042-0.4151No
45PDE6GPDE6G
Entrez,  Source
phosphodiesterase 6G, cGMP-specific, rod, gamma12768-0.043-0.4137No
46HSPG2HSPG2
Entrez,  Source
heparan sulfate proteoglycan 2 (perlecan)13070-0.046-0.4212No
47OPN1SWOPN1SW
Entrez,  Source
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)13163-0.048-0.4183No
48GPC3GPC3
Entrez,  Source
glypican 313576-0.052-0.4304No
49LRP2LRP2
Entrez,  Source
low density lipoprotein-related protein 213809-0.054-0.4333No
50PPEF1PPEF1
Entrez,  Source
protein phosphatase, EF-hand calcium binding domain 114300-0.060-0.4478No
51TTRTTR
Entrez,  Source
transthyretin (prealbumin, amyloidosis type I)14523-0.063-0.4489No
52PDE6APDE6A
Entrez,  Source
phosphodiesterase 6A, cGMP-specific, rod, alpha14877-0.067-0.4557No
53CHRM1CHRM1
Entrez,  Source
cholinergic receptor, muscarinic 115122-0.070-0.4567Yes
54APOA2APOA2
Entrez,  Source
apolipoprotein A-II15193-0.071-0.4491Yes
55GPC4GPC4
Entrez,  Source
glypican 415233-0.072-0.4399Yes
56PDCPDC
Entrez,  Source
phosducin15498-0.075-0.4411Yes
57RBP1RBP1
Entrez,  Source
retinol binding protein 1, cellular15710-0.078-0.4392Yes
58GUCY2FGUCY2F
Entrez,  Source
guanylate cyclase 2F, retinal15774-0.079-0.4301Yes
59RHORHO
Entrez,  Source
rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)15830-0.080-0.4204Yes
60METAP1METAP1
Entrez,  Source
methionyl aminopeptidase 116000-0.082-0.4158Yes
61RPE65RPE65
Entrez,  Source
retinal pigment epithelium-specific protein 65kDa16030-0.083-0.4044Yes
62GUCA1AGUCA1A
Entrez,  Source
guanylate cyclase activator 1A (retina)16032-0.083-0.3917Yes
63CNGB1CNGB1
Entrez,  Source
cyclic nucleotide gated channel beta 116291-0.086-0.3909Yes
64RCVRNRCVRN
Entrez,  Source
recoverin16460-0.089-0.3853Yes
65GUCA1CGUCA1C
Entrez,  Source
guanylate cyclase activator 1C16462-0.089-0.3716Yes
66GNGT1GNGT1
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 116470-0.089-0.3582Yes
67RDH12RDH12
Entrez,  Source
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)16695-0.093-0.3548Yes
68NR2E3NR2E3
Entrez,  Source
nuclear receptor subfamily 2, group E, member 316754-0.093-0.3432Yes
69APOC2APOC2
Entrez,  Source
apolipoprotein C-II17026-0.098-0.3413Yes
70GPC1GPC1
Entrez,  Source
glypican 117530-0.106-0.3495Yes
71RBP2RBP2
Entrez,  Source
retinol binding protein 2, cellular17713-0.109-0.3415Yes
72GPC2GPC2
Entrez,  Source
glypican 2 (cerebroglycan)17887-0.112-0.3326Yes
73AKR1C1AKR1C1
Entrez,  Source
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)17952-0.113-0.3182Yes
74AKR1B10AKR1B10
Entrez,  Source
aldo-keto reductase family 1, member B10 (aldose reductase)18125-0.117-0.3086Yes
75APOBAPOB
Entrez,  Source
apolipoprotein B (including Ag(x) antigen)18249-0.119-0.2961Yes
76APOC3APOC3
Entrez,  Source
apolipoprotein C-III18608-0.127-0.2940Yes
77GRK1GRK1
Entrez,  Source
G protein-coupled receptor kinase 118652-0.128-0.2763Yes
78LPLLPL
Entrez,  Source
lipoprotein lipase18752-0.130-0.2610Yes
79APOA4APOA4
Entrez,  Source
apolipoprotein A-IV18900-0.134-0.2475Yes
80CLPSCLPS
Entrez,  Source
colipase, pancreatic18985-0.136-0.2305Yes
81PITPNM1PITPNM1
Entrez,  Source
phosphatidylinositol transfer protein, membrane-associated 119008-0.137-0.2105Yes
82GPC6GPC6
Entrez,  Source
glypican 619307-0.146-0.2024Yes
83PDE6BPDE6B
Entrez,  Source
phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant)19391-0.149-0.1834Yes
84GNAT1GNAT1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 119570-0.156-0.1680Yes
85RGS9RGS9
Entrez,  Source
regulator of G-protein signalling 919644-0.159-0.1470Yes
86ABCA4ABCA4
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 419805-0.166-0.1291Yes
87RDH5RDH5
Entrez,  Source
retinol dehydrogenase 5 (11-cis/9-cis)19875-0.170-0.1062Yes
88APOA1APOA1
Entrez,  Source
apolipoprotein A-I20163-0.190-0.0909Yes
89PRKCQPRKCQ
Entrez,  Source
protein kinase C, theta20368-0.215-0.0676Yes
90AKR1C3AKR1C3
Entrez,  Source
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)20499-0.239-0.0369Yes
91DHRS3DHRS3
Entrez,  Source
dehydrogenase/reductase (SDR family) member 320576-0.2720.0014Yes
Table: GSEA details [plain text format]



Fig 2: PHOTOTRANSDUCTION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHOTOTRANSDUCTION: Random ES distribution   
Gene set null distribution of ES for PHOTOTRANSDUCTION