Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classY
GeneSetACTIVATION OF ADENYLATE CYCLASE ACTIVITY
Enrichment Score (ES)-0.6079185
Normalized Enrichment Score (NES)-1.7885654
Nominal p-value0.0042462847
FDR q-value0.4373078
FWER p-Value0.946
Table: GSEA Results Summary



Fig 1: Enrichment plot: ACTIVATION OF ADENYLATE CYCLASE ACTIVITY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor20070.112-0.0526No
2CAP1CAP1
Entrez,  Source
CAP, adenylate cyclase-associated protein 1 (yeast)48300.054-0.1681No
3PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha53950.045-0.1774No
4EDNRAEDNRA
Entrez,  Source
endothelin receptor type A85320.004-0.3282No
5GNASGNAS
Entrez,  Source
GNAS complex locus8949-0.001-0.3480No
6NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 210742-0.021-0.4267No
7ADORA2AADORA2A
Entrez,  Source
adenosine A2a receptor12918-0.045-0.5144No
8DRD1DRD1
Entrez,  Source
dopamine receptor D112921-0.045-0.4964No
9GLP1RGLP1R
Entrez,  Source
glucagon-like peptide 1 receptor14676-0.065-0.5556No
10ADCYAP1ADCYAP1
Entrez,  Source
adenylate cyclase activating polypeptide 1 (pituitary)14782-0.066-0.5342No
11DRD5DRD5
Entrez,  Source
dopamine receptor D515191-0.071-0.5254No
12LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor16890-0.095-0.5696Yes
13ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor17471-0.105-0.5558Yes
14ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface18267-0.119-0.5464Yes
15CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)18305-0.120-0.4999Yes
16ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor18534-0.125-0.4607Yes
17ADCYAP1R1ADCYAP1R1
Entrez,  Source
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I18920-0.134-0.4255Yes
18AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)19482-0.152-0.3916Yes
19ACRACR
Entrez,  Source
acrosin19701-0.161-0.3375Yes
20CRHR1CRHR1
Entrez,  Source
corticotropin releasing hormone receptor 119792-0.165-0.2755Yes
21CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha19817-0.167-0.2097Yes
22GIPRGIPR
Entrez,  Source
gastric inhibitory polypeptide receptor19823-0.167-0.1428Yes
23NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 120338-0.211-0.0831Yes
24P2RY11P2RY11
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 1120500-0.2390.0051Yes
Table: GSEA details [plain text format]



Fig 2: ACTIVATION OF ADENYLATE CYCLASE ACTIVITY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ACTIVATION OF ADENYLATE CYCLASE ACTIVITY: Random ES distribution   
Gene set null distribution of ES for ACTIVATION OF ADENYLATE CYCLASE ACTIVITY