Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classY
GeneSetPOSITIVE REGULATION OF ADENYLATE CYCLASE ACTIVITY
Enrichment Score (ES)-0.60455793
Normalized Enrichment Score (NES)-1.8619633
Nominal p-value0.0041237115
FDR q-value0.49169543
FWER p-Value0.772
Table: GSEA Results Summary



Fig 1: Enrichment plot: POSITIVE REGULATION OF ADENYLATE CYCLASE ACTIVITY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor20070.112-0.0550No
2CAP1CAP1
Entrez,  Source
CAP, adenylate cyclase-associated protein 1 (yeast)48300.054-0.1716No
3PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha53950.045-0.1818No
4VIPVIP
Entrez,  Source
vasoactive intestinal peptide69320.024-0.2472No
5EDNRAEDNRA
Entrez,  Source
endothelin receptor type A85320.004-0.3234No
6GNASGNAS
Entrez,  Source
GNAS complex locus8949-0.001-0.3433No
7NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)10093-0.013-0.3937No
8NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 210742-0.021-0.4173No
9ADORA2AADORA2A
Entrez,  Source
adenosine A2a receptor12918-0.045-0.5059No
10DRD1DRD1
Entrez,  Source
dopamine receptor D112921-0.045-0.4888No
11GLP1RGLP1R
Entrez,  Source
glucagon-like peptide 1 receptor14676-0.065-0.5494No
12ADCYAP1ADCYAP1
Entrez,  Source
adenylate cyclase activating polypeptide 1 (pituitary)14782-0.066-0.5293No
13DRD5DRD5
Entrez,  Source
dopamine receptor D515191-0.071-0.5220No
14LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor16890-0.095-0.5682Yes
15CALCRCALCR
Entrez,  Source
calcitonin receptor17044-0.098-0.5384Yes
16ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor17471-0.105-0.5193Yes
17ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface18267-0.119-0.5124Yes
18CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)18305-0.120-0.4683Yes
19ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor18534-0.125-0.4317Yes
20ADCYAP1R1ADCYAP1R1
Entrez,  Source
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I18920-0.134-0.3993Yes
21AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)19482-0.152-0.3686Yes
22ACRACR
Entrez,  Source
acrosin19701-0.161-0.3178Yes
23CRHR1CRHR1
Entrez,  Source
corticotropin releasing hormone receptor 119792-0.165-0.2593Yes
24CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha19817-0.167-0.1969Yes
25GIPRGIPR
Entrez,  Source
gastric inhibitory polypeptide receptor19823-0.167-0.1335Yes
26NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 120338-0.211-0.0781Yes
27P2RY11P2RY11
Entrez,  Source
purinergic receptor P2Y, G-protein coupled, 1120500-0.2390.0051Yes
Table: GSEA details [plain text format]



Fig 2: POSITIVE REGULATION OF ADENYLATE CYCLASE ACTIVITY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: POSITIVE REGULATION OF ADENYLATE CYCLASE ACTIVITY: Random ES distribution   
Gene set null distribution of ES for POSITIVE REGULATION OF ADENYLATE CYCLASE ACTIVITY