Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | gse25507_collapsed_to_symbols.gse25507.gpl570.cls #N_versus_Y.gse25507.gpl570.cls #N_versus_Y_repos |
| Phenotype | gse25507.gpl570.cls#N_versus_Y_repos |
| Upregulated in class | Y |
| GeneSet | ACTIVATION OF ADENYLATE CYCLASE ACTIVITY |
| Enrichment Score (ES) | -0.6079185 |
| Normalized Enrichment Score (NES) | -1.7885654 |
| Nominal p-value | 0.0042462847 |
| FDR q-value | 0.4373078 |
| FWER p-Value | 0.946 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ADRB1 | ADRB1 Entrez, Source | adrenergic, beta-1-, receptor | 2007 | 0.112 | -0.0526 | No |
| 2 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 4830 | 0.054 | -0.1681 | No |
| 3 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 5395 | 0.045 | -0.1774 | No |
| 4 | EDNRA | EDNRA Entrez, Source | endothelin receptor type A | 8532 | 0.004 | -0.3282 | No |
| 5 | GNAS | GNAS Entrez, Source | GNAS complex locus | 8949 | -0.001 | -0.3480 | No |
| 6 | NTRK2 | NTRK2 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 2 | 10742 | -0.021 | -0.4267 | No |
| 7 | ADORA2A | ADORA2A Entrez, Source | adenosine A2a receptor | 12918 | -0.045 | -0.5144 | No |
| 8 | DRD1 | DRD1 Entrez, Source | dopamine receptor D1 | 12921 | -0.045 | -0.4964 | No |
| 9 | GLP1R | GLP1R Entrez, Source | glucagon-like peptide 1 receptor | 14676 | -0.065 | -0.5556 | No |
| 10 | ADCYAP1 | ADCYAP1 Entrez, Source | adenylate cyclase activating polypeptide 1 (pituitary) | 14782 | -0.066 | -0.5342 | No |
| 11 | DRD5 | DRD5 Entrez, Source | dopamine receptor D5 | 15191 | -0.071 | -0.5254 | No |
| 12 | LHCGR | LHCGR Entrez, Source | luteinizing hormone/choriogonadotropin receptor | 16890 | -0.095 | -0.5696 | Yes |
| 13 | ADRB3 | ADRB3 Entrez, Source | adrenergic, beta-3-, receptor | 17471 | -0.105 | -0.5558 | Yes |
| 14 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 18267 | -0.119 | -0.5464 | Yes |
| 15 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 18305 | -0.120 | -0.4999 | Yes |
| 16 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 18534 | -0.125 | -0.4607 | Yes |
| 17 | ADCYAP1R1 | ADCYAP1R1 Entrez, Source | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | 18920 | -0.134 | -0.4255 | Yes |
| 18 | AVPR2 | AVPR2 Entrez, Source | arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) | 19482 | -0.152 | -0.3916 | Yes |
| 19 | ACR | ACR Entrez, Source | acrosin | 19701 | -0.161 | -0.3375 | Yes |
| 20 | CRHR1 | CRHR1 Entrez, Source | corticotropin releasing hormone receptor 1 | 19792 | -0.165 | -0.2755 | Yes |
| 21 | CALCA | CALCA Entrez, Source | calcitonin/calcitonin-related polypeptide, alpha | 19817 | -0.167 | -0.2097 | Yes |
| 22 | GIPR | GIPR Entrez, Source | gastric inhibitory polypeptide receptor | 19823 | -0.167 | -0.1428 | Yes |
| 23 | NTRK1 | NTRK1 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 1 | 20338 | -0.211 | -0.0831 | Yes |
| 24 | P2RY11 | P2RY11 Entrez, Source | purinergic receptor P2Y, G-protein coupled, 11 | 20500 | -0.239 | 0.0051 | Yes |
