Datasetgse25507_collapsed_to_symbols.gse25507.gpl570.cls
#N_versus_Y.gse25507.gpl570.cls
#N_versus_Y_repos
Phenotypegse25507.gpl570.cls#N_versus_Y_repos
Upregulated in classN
GeneSetVESICLE COATING
Enrichment Score (ES)0.51370686
Normalized Enrichment Score (NES)1.6995811
Nominal p-value0.005952381
FDR q-value1.0
FWER p-Value0.998
Table: GSEA Results Summary



Fig 1: Enrichment plot: VESICLE COATING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SEC24BSEC24B
Entrez,  Source
SEC24 related gene family, member B (S. cerevisiae)750.2410.0431Yes
2RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family3640.1890.0657Yes
3COPECOPE
Entrez,  Source
coatomer protein complex, subunit epsilon4510.1800.0964Yes
4CNIH3CNIH3
Entrez,  Source
cornichon homolog 3 (Drosophila)5300.1740.1263Yes
5F8F8
Entrez,  Source
coagulation factor VIII, procoagulant component (hemophilia A)6100.1690.1551Yes
6NAPANAPA
Entrez,  Source
N-ethylmaleimide-sensitive factor attachment protein, alpha11530.1400.1558Yes
7FCHO2FCHO2
Entrez,  Source
FCH domain only 211680.1390.1820Yes
8TRAPPC1TRAPPC1
Entrez,  Source
trafficking protein particle complex 115000.1270.1905Yes
9BET1BET1
Entrez,  Source
BET1 homolog (S. cerevisiae)16440.1230.2073Yes
10TMED2TMED2
Entrez,  Source
transmembrane emp24 domain trafficking protein 216600.1220.2303Yes
11AP2S1AP2S1
Entrez,  Source
adaptor-related protein complex 2, sigma 1 subunit19000.1140.2408Yes
12CTSZCTSZ
Entrez,  Source
cathepsin Z19150.1140.2623Yes
13TRAPPC6BTRAPPC6B
Entrez,  Source
trafficking protein particle complex 6B20880.1090.2751Yes
14CD59CD59
Entrez,  Source
CD59 molecule, complement regulatory protein22000.1060.2903Yes
15SEC23IPSEC23IP
Entrez,  Source
SEC23 interacting protein22360.1050.3089Yes
16SEC22BSEC22B
Entrez,  Source
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)23530.1020.3231Yes
17MCFD2MCFD2
Entrez,  Source
multiple coagulation factor deficiency 223860.1020.3413Yes
18SEC23ASEC23A
Entrez,  Source
Sec23 homolog A (S. cerevisiae)25690.0970.3513Yes
19TRAPPC5TRAPPC5
Entrez,  Source
trafficking protein particle complex 525770.0970.3698Yes
20COPB2COPB2
Entrez,  Source
coatomer protein complex, subunit beta 2 (beta prime)26720.0950.3836Yes
21PIK3C2APIK3C2A
Entrez,  Source
phosphoinositide-3-kinase, class 2, alpha polypeptide28610.0910.3920Yes
22F5F5
Entrez,  Source
coagulation factor V (proaccelerin, labile factor)29730.0880.4037Yes
23TGFATGFA
Entrez,  Source
transforming growth factor, alpha32590.0830.4059Yes
24SEC24DSEC24D
Entrez,  Source
SEC24 related gene family, member D (S. cerevisiae)32710.0820.4213Yes
25SEC24ASEC24A
Entrez,  Source
SEC24 related gene family, member A (S. cerevisiae)32730.0820.4372Yes
26TRAPPC3TRAPPC3
Entrez,  Source
trafficking protein particle complex 333260.0810.4504Yes
27SAR1BSAR1B
Entrez,  Source
SAR1 gene homolog B (S. cerevisiae)34370.0790.4604Yes
28HIP1HIP1
Entrez,  Source
huntingtin interacting protein 135080.0780.4721Yes
29SCFD1SCFD1
Entrez,  Source
sec1 family domain containing 135530.0770.4848Yes
30TRAPPC2TRAPPC2
Entrez,  Source
trafficking protein particle complex 236630.0750.4940Yes
31NSFNSF
Entrez,  Source
N-ethylmaleimide-sensitive factor37190.0730.5055Yes
32COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha38350.0710.5137Yes
33KLHL12KLHL12
Entrez,  Source
kelch-like 12 (Drosophila)42520.0630.5057No
34EPS15EPS15
Entrez,  Source
epidermal growth factor receptor pathway substrate 1548400.0540.4875No
35PICALMPICALM
Entrez,  Source
phosphatidylinositol binding clathrin assembly protein50890.0500.4851No
36SERPINA1SERPINA1
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 152090.0480.4886No
37TMED9TMED9
Entrez,  Source
transmembrane emp24 protein transport domain containing 952530.0470.4957No
38TRAPPC6ATRAPPC6A
Entrez,  Source
trafficking protein particle complex 6A59050.0380.4713No
39CSNK1DCSNK1D
Entrez,  Source
casein kinase 1, delta60130.0360.4732No
40RAB1BRAB1B
Entrez,  Source
RAB1B, member RAS oncogene family61030.0350.4757No
41COPB1COPB1
Entrez,  Source
coatomer protein complex, subunit beta 169660.0240.4383No
42TFGTFG
Entrez,  Source
TRK-fused gene73920.0180.4212No
43TRAPPC2LTRAPPC2L
Entrez,  Source
trafficking protein particle complex 2-like77470.0140.4067No
44FOLR1FOLR1
Entrez,  Source
folate receptor 1 (adult)78560.0130.4039No
45TRAPPC4TRAPPC4
Entrez,  Source
trafficking protein particle complex 481800.0080.3898No
46SEC31ASEC31A
Entrez,  Source
SEC31 homolog A (S. cerevisiae)86310.0030.3684No
47AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)87060.0020.3652No
48GOLGA2GOLGA2
Entrez,  Source
golgi autoantigen, golgin subfamily a, 29199-0.0040.3420No
49ARF1ARF1
Entrez,  Source
ADP-ribosylation factor 19245-0.0040.3406No
50FCHO1FCHO1
Entrez,  Source
FCH domain only 19652-0.0080.3224No
51TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)9658-0.0090.3239No
52PPP6CPPP6C
Entrez,  Source
protein phosphatase 6, catalytic subunit9978-0.0120.3107No
53LMAN1LMAN1
Entrez,  Source
lectin, mannose-binding, 110286-0.0150.2987No
54ANKRD28ANKRD28
Entrez,  Source
ankyrin repeat domain 2810295-0.0160.3013No
55ARCN1ARCN1
Entrez,  Source
archain 110472-0.0180.2962No
56CUL3CUL3
Entrez,  Source
cullin 310774-0.0210.2856No
57GORASP1GORASP1
Entrez,  Source
golgi reassembly stacking protein 1, 65kDa11260-0.0260.2671No
58GBF1GBF1
Entrez,  Source
golgi-specific brefeldin A resistance factor 111953-0.0340.2401No
59CNIH2CNIH2
Entrez,  Source
cornichon homolog 2 (Drosophila)12922-0.0450.2017No
60COPZ1COPZ1
Entrez,  Source
coatomer protein complex, subunit zeta 113522-0.0510.1825No
61CTSCCTSC
Entrez,  Source
cathepsin C15317-0.0730.1093No
62COL7A1COL7A1
Entrez,  Source
collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive)15720-0.0780.1049No
63GOSR2GOSR2
Entrez,  Source
golgi SNAP receptor complex member 216666-0.0920.0767No
64GRIA1GRIA1
Entrez,  Source
glutamate receptor, ionotropic, AMPA 116920-0.0960.0830No
65SEC24CSEC24C
Entrez,  Source
SEC24 related gene family, member C (S. cerevisiae)17684-0.1080.0668No
66PREBPREB
Entrez,  Source
prolactin regulatory element binding17766-0.1100.0842No
67STX5STX5
Entrez,  Source
syntaxin 518695-0.1290.0640No
68ARFGAP1ARFGAP1
Entrez,  Source
ADP-ribosylation factor GTPase activating protein 119414-0.1490.0580No
Table: GSEA details [plain text format]



Fig 2: VESICLE COATING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VESICLE COATING: Random ES distribution   
Gene set null distribution of ES for VESICLE COATING