Genes in this set(11):
| Std. name | Sys. name | SGDID |
| RAD18 | YCR066W | S000000662 |
| RAD51 | YER095W | S000000897 |
| RAD57 | YDR004W | S000002411 |
| XRS2 | YDR369C | S000002777 |
| RAD5 | YLR032W | S000004022 |
| MEC3 | YLR288C | S000004279 |
| PAH1 | YMR165C | S000004775 |
| PPA2 | YMR267W | S000004880 |
| | YNL086W | S000005030 |
| RAD17 | YOR368W | S000005895 |
| GLR1 | YPL091W | S000006012 |
Enriched GO terms in this set:
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0050896 (response to stimulus)
"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."
GO:0006950 (response to stress) [p = 0.004 (8/237: RAD18; RAD51; RAD57; XRS2; RAD5; MEC3; RAD17; GLR1)]
"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)."
GO:0006974 (response to DNA damage stimulus) [p < 0.001 (7/120: RAD18; RAD51; RAD57; XRS2; RAD5; MEC3; RAD17)]
"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism."
GO:0006281 (DNA repair) [p = 0.001 (6/88: RAD18; RAD51; RAD57; XRS2; RAD5; RAD17)]
"The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway."
GO:0006302 (double-strand break repair) [p < 0.001 (5/34: RAD51; RAD57; XRS2; RAD5; RAD17)]
"The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding)
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding)
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p < 0.001 (4/19: RAD18; XRS2; RAD5; RAD17)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0032200 (telomere organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that includes the telomeric DNA repeats and associated proteins."
GO:0000723 (telomere maintenance)
"The maintenance of proper telomeric length and structure by processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA. These processes includes those that shorten and lengthen the telomeric DNA sequences."
GO:0000722 (telomere maintenance via recombination) [p = 0.004 (3/8: RAD51; RAD57; MEC3)]
"The maintenance of proper telomeric length by recombinational processes."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p = 0.004 (5/62: RAD51; RAD57; XRS2; MEC3; RAD17)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0007131 (meiotic recombination) [p = 0.004 (4/28: RAD51; RAD57; XRS2; RAD17)]
"The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003824 (catalytic activity)
"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."
GO:0016787 (hydrolase activity)
"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."
GO:0016817 (hydrolase activity, acting on acid anhydrides)
"Catalysis of the hydrolysis of any acid anhydride."
GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)
"Catalysis of the hydrolysis of any acid anhydride which contains phosphorus."
GO:0016462 (pyrophosphatase activity)
"Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments."
GO:0017111 (nucleoside-triphosphatase activity)
"Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate."
GO:0016887 (ATPase activity)
"Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction."
GO:0042623 (ATPase activity, coupled)
"Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane."
GO:0008094 (DNA-dependent ATPase activity) [p = 0.009 (3/11: RAD18; RAD51; RAD57)]
"Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction."
---