Genes in this set(15):
| Std. name | Sys. name | SGDID |
| SPT7 | YBR081C | S000000285 |
| PAF1 | YBR279W | S000000483 |
| SRB2 | YHR041C | S000001083 |
| SET1 | YHR119W | S000001161 |
| SDS3 | YIL084C | S000001346 |
| NAP1 | YKR048C | S000001756 |
| MED2 | YDL005C | S000002163 |
| NGG1 | YDR176W | S000002583 |
| PGD1 | YGL025C | S000002993 |
| GCN5 | YGR252W | S000003484 |
| HHT2 | YNL031C | S000004976 |
| PHO23 | YNL097C | S000005041 |
| RPD3 | YNL330C | S000005274 |
| SIN3 | YOL004W | S000005364 |
| CTR9 | YOL145C | S000005505 |
Enriched GO terms in this set:
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part) [p < 0.001 (14/304: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0005654 (nucleoplasm) [p < 0.001 (13/135: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"That part of the nuclear content other than the chromosomes or the nucleolus."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part) [p < 0.001 (14/304: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0031981 (nuclear lumen) [p < 0.001 (13/171: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"The volume enclosed by the nuclear inner membrane."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0016043 (cellular component organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component; includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
GO:0006996 (organelle organization and biogenesis) [p < 0.001 (14/580: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of any organelle within a cell."
GO:0051276 (chromosome organization and biogenesis) [p < 0.001 (14/333: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"A process that is carried out at the cellular level that results in the formation, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0043226 (organelle)
"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."
GO:0043227 (membrane-bound organelle)
"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane."
GO:0043231 (intracellular membrane-bound organelle)
"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane."
GO:0005634 (nucleus) [p < 0.001 (15/570: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part) [p < 0.001 (14/304: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0044451 (nucleoplasm part) [p < 0.001 (13/127: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus."
GO:0016591 (DNA-directed RNA polymerase II, holoenzyme) [p < 0.001 (5/19: PAF1; SRB2; MED2; PGD1; CTR9)]
"Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part) [p < 0.001 (14/304: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0044451 (nucleoplasm part) [p < 0.001 (13/127: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus."
GO:0005667 (transcription factor complex) [p < 0.001 (7/59: SPT7; SDS3; NGG1; GCN5; PHO23; RPD3; SIN3)]
"Any complex, distinct from RNA polymerase, including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences, and regulating transcription."
GO:0000118 (histone deacetylase complex) [p = 0.003 (4/20: SDS3; PHO23; RPD3; SIN3)]
"Complex that possesses histone deacetylase activity."
GO:0000508 (Rpd3L complex) [p < 0.001 (4/9: SDS3; PHO23; RPD3; SIN3)]
"A multisubunit histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0016043 (cellular component organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component; includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
GO:0006996 (organelle organization and biogenesis) [p < 0.001 (14/580: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of any organelle within a cell."
GO:0051276 (chromosome organization and biogenesis) [p < 0.001 (14/333: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"A process that is carried out at the cellular level that results in the formation, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information."
GO:0006325 (establishment and/or maintenance of chromatin architecture) [p < 0.001 (12/137: SPT7; PAF1; SET1; SDS3; NAP1; NGG1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"The specification, formation and maintenance of the physical structure of eukaryotic chromatin."
GO:0006333 (chromatin assembly or disassembly) [p = 0.002 (6/66: SET1; SDS3; NAP1; HHT2; RPD3; SIN3)]
"The formation or destruction of chromatin structures."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0008152 (metabolic process)
"Processes that cause many of the chemical changes in living organisms, including anabolism and catabolism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation."
GO:0043170 (macromolecule metabolic process)
"The chemical reactions and pathways involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates."
GO:0043283 (biopolymer metabolic process) [p = 0.001 (15/737: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins."
GO:0043412 (biopolymer modification) [p = 0.002 (10/257: SPT7; PAF1; SET1; SDS3; NGG1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties."
GO:0006464 (protein modification process) [p = 0.001 (10/240: SPT7; PAF1; SET1; SDS3; NGG1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)."
GO:0043687 (post-translational protein modification) [p < 0.001 (10/187: SPT7; PAF1; SET1; SDS3; NGG1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome."
GO:0006476 (protein amino acid deacetylation) [p = 0.002 (4/18: SDS3; PHO23; RPD3; SIN3)]
"The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid."
GO:0016575 (histone deacetylation) [p = 0.002 (4/18: SDS3; PHO23; RPD3; SIN3)]
"The modification of histones by removal of acetyl groups."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (15/568: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006350 (transcription) [p = 0.003 (9/222: PAF1; SRB2; SET1; SDS3; MED2; PGD1; RPD3; SIN3; CTR9)]
"The synthesis of either RNA on a template of DNA or DNA on a template of RNA."
GO:0006351 (transcription, DNA-dependent) [p = 0.002 (9/208: PAF1; SRB2; SET1; SDS3; MED2; PGD1; RPD3; SIN3; CTR9)]
"The synthesis of RNA on a template of DNA."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part) [p < 0.001 (14/304: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0044451 (nucleoplasm part) [p < 0.001 (13/127: SPT7; PAF1; SRB2; SET1; SDS3; MED2; NGG1; PGD1; GCN5; PHO23; RPD3; SIN3; CTR9)]
"Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus."
GO:0000119 (mediator complex) [p = 0.010 (3/9: SRB2; MED2; PGD1)]
"A protein complex that enables the RNA polymerase II-general RNA polymerase II transcription factor complex to react to transcriptional activator proteins; also enhances the level of basal transcription."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0016043 (cellular component organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component; includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
GO:0006996 (organelle organization and biogenesis) [p < 0.001 (14/580: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of any organelle within a cell."
GO:0051276 (chromosome organization and biogenesis) [p < 0.001 (14/333: SPT7; PAF1; SRB2; SET1; SDS3; NAP1; NGG1; PGD1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"A process that is carried out at the cellular level that results in the formation, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information."
GO:0006325 (establishment and/or maintenance of chromatin architecture) [p < 0.001 (12/137: SPT7; PAF1; SET1; SDS3; NAP1; NGG1; GCN5; HHT2; PHO23; RPD3; SIN3; CTR9)]
"The specification, formation and maintenance of the physical structure of eukaryotic chromatin."
GO:0006333 (chromatin assembly or disassembly) [p = 0.002 (6/66: SET1; SDS3; NAP1; HHT2; RPD3; SIN3)]
"The formation or destruction of chromatin structures."
GO:0031497 (chromatin assembly)
"The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus."
GO:0031507 (heterochromatin formation)
"The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent."
GO:0006342 (chromatin silencing)
"Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin."
GO:0000183 (chromatin silencing at rDNA) [p = 0.010 (3/9: SET1; RPD3; SIN3)]
"Repression of transcription of ribosomal DNA by the formation of heterochromatin."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0005515 (protein binding)
"Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)."
GO:0008134 (transcription factor binding) [p = 0.003 (4/20: NGG1; GCN5; RPD3; SIN3)]
"Interacting selectively with a transcription factor, any protein required to initiate or regulate transcription."
GO:0003712 (transcription cofactor activity) [p = 0.002 (4/19: NGG1; GCN5; RPD3; SIN3)]
"The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself."
GO:0003713 (transcription coactivator activity) [p = 0.010 (3/9: GCN5; RPD3; SIN3)]
"The function of a transcription cofactor that activates transcription from a RNA polymerase II promoter; does not bind DNA itself."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0030528 (transcription regulator activity) [p < 0.001 (9/120: PAF1; SRB2; MED2; NGG1; PGD1; GCN5; RPD3; SIN3; CTR9)]
"Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor."
GO:0003702 (RNA polymerase II transcription factor activity)
"Functions to initiate or regulate RNA polymerase II transcription."
GO:0016251 (general RNA polymerase II transcription factor activity)
"Any function that supports basal (unregulated) transcription of genes by core RNA polymerase II. Five general transcription factors are necessary and sufficient for such basal transcription in yeast: TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBF)."
GO:0016455 (RNA polymerase II transcription mediator activity) [p = 0.010 (3/9: SRB2; MED2; PGD1)]
"Functions to mediate the interaction of transcriptional activators with the RNA polymerase II-general RNA polymerase II transcription factor complex."
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