Genes in this set(4):
| Std. name | Sys. name | SGDID |
| PTC3 | YBL056W | S000000152 |
| PTP3 | YER075C | S000000877 |
| PTC2 | YER089C | S000000891 |
| MKK1 | YOR231W | S000005757 |
Enriched GO terms in this set:
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0065007 (biological regulation)
"Any process that modulates the frequency, rate or extent of any biological process, quality or function."
GO:0065009 (regulation of a molecular function)
"Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding."
GO:0050790 (regulation of catalytic activity)
"Any process that modulates the activity of an enzyme."
GO:0051338 (regulation of transferase activity) [p = 0.003 (3/25: PTC3; PTP3; PTC2)]
"Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2."
GO:0043549 (regulation of kinase activity) [p = 0.003 (3/24: PTC3; PTP3; PTC2)]
"Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."
GO:0045859 (regulation of protein kinase activity) [p = 0.003 (3/24: PTC3; PTP3; PTC2)]
"Any process that modulates the frequency, rate or extent of protein kinase activity."
GO:0043405 (regulation of MAP kinase activity) [p < 0.001 (3/6: PTC3; PTP3; PTC2)]
"Any process that modulates the frequency, rate or extent of MAP kinase activity."
GO:0043407 (negative regulation of MAP kinase activity) [p < 0.001 (3/5: PTC3; PTP3; PTC2)]
"Any process that stops, prevents or reduces the frequency, rate or extent of MAP kinase activity."
GO:0000188 (inactivation of MAPK activity) [p < 0.001 (3/5: PTC3; PTP3; PTC2)]
"Any process that terminates the activity of the active enzyme MAP kinase."
GO:0000173 (inactivation of MAPK activity during osmolarity sensing) [p < 0.001 (3/5: PTC3; PTP3; PTC2)]
"Any process that terminates the activity of the active enzyme MAP kinase during osmolarity sensing."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0065007 (biological regulation)
"Any process that modulates the frequency, rate or extent of any biological process, quality or function."
GO:0065009 (regulation of a molecular function)
"Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding."
GO:0050790 (regulation of catalytic activity)
"Any process that modulates the activity of an enzyme."
GO:0043086 (negative regulation of catalytic activity) [p < 0.001 (3/10: PTC3; PTP3; PTC2)]
"Any process that stops or reduces the activity of an enzyme."
GO:0051348 (negative regulation of transferase activity) [p < 0.001 (3/7: PTC3; PTP3; PTC2)]
"Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0007154 (cell communication) [p = 0.007 (4/119: PTC3; PTP3; PTC2; MKK1)]
"Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."
GO:0007165 (signal transduction) [p = 0.007 (4/114: PTC3; PTP3; PTC2; MKK1)]
"The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell."
GO:0007242 (intracellular signaling cascade)
"A series of reactions within the cell that occur as a result of a single trigger reaction or compound."
GO:0007243 (protein kinase cascade) [p = 0.001 (3/16: PTC3; PTP3; PTC2)]
"A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound."
GO:0000165 (MAPKKK cascade) [p < 0.001 (3/14: PTC3; PTP3; PTC2)]
"Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways."
GO:0000161 (MAPKKK cascade during osmolarity sensing) [p < 0.001 (3/10: PTC3; PTP3; PTC2)]
"MAPKKK cascade involved in signal transduction in response to change in osmotic conditions."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006793 (phosphorus metabolic process) [p = 0.003 (4/92: PTC3; PTP3; PTC2; MKK1)]
"The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)."
GO:0006796 (phosphate metabolic process) [p = 0.003 (4/92: PTC3; PTP3; PTC2; MKK1)]
"The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid."
GO:0016311 (dephosphorylation) [p = 0.003 (3/23: PTC3; PTP3; PTC2)]
"The process of removing one or more phosphoric (ester or anhydride) residues from a molecule."
GO:0006470 (protein amino acid dephosphorylation) [p = 0.001 (3/15: PTC3; PTP3; PTC2)]
"The process of removing one or more phosphoric residues from a protein."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0007154 (cell communication) [p = 0.007 (4/119: PTC3; PTP3; PTC2; MKK1)]
"Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment."
GO:0007165 (signal transduction) [p = 0.007 (4/114: PTC3; PTP3; PTC2; MKK1)]
"The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell."
GO:0007166 (cell surface receptor linked signal transduction) [p = 0.007 (3/27: PTC3; PTP3; PTC2)]
"Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell."
GO:0007231 (osmosensory signaling pathway) [p = 0.001 (3/17: PTC3; PTP3; PTC2)]
"The series of molecular signals initiated in response to osmotic change."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003824 (catalytic activity)
"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."
GO:0016787 (hydrolase activity)
"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."
GO:0016788 (hydrolase activity, acting on ester bonds)
"Catalysis of the hydrolysis of any ester bond."
GO:0042578 (phosphoric ester hydrolase activity)
"Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3."
GO:0016791 (phosphoric monoester hydrolase activity)
"Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."
GO:0004721 (phosphoprotein phosphatase activity) [p = 0.003 (3/22: PTC3; PTP3; PTC2)]
"Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity."
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