Genes in this set(16):
| Std. name | Sys. name | SGDID |
| SEC66 | YBR171W | S000000375 |
| MSI1 | YBR195C | S000000399 |
| RAD18 | YCR066W | S000000662 |
| RAD24 | YER173W | S000000975 |
| MET18 | YIL128W | S000001390 |
| RAD55 | YDR076W | S000002483 |
| RAD9 | YDR217C | S000002625 |
| XRS2 | YDR369C | S000002777 |
| RAD54 | YGL163C | S000003131 |
| TOP3 | YLR234W | S000004224 |
| | YLR235C | S000004225 |
| RAD52 | YML032C | S000004494 |
| RAD17 | YOR368W | S000005895 |
| RMI1 | YPL024W | S000005945 |
| BRO1 | YPL084W | S000006005 |
| DDC1 | YPL194W | S000006115 |
Enriched GO terms in this set:
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (13/384: MSI1; RAD18; RAD24; MET18; RAD55; RAD9; XRS2; RAD54; TOP3; RAD52; RAD17; BRO1; DDC1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (8/62: RAD24; RAD55; XRS2; RAD54; TOP3; RAD52; RAD17; DDC1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0007131 (meiotic recombination) [p < 0.001 (6/28: RAD24; RAD55; XRS2; TOP3; RAD52; RAD17)]
"The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process)
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase)
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0007127 (meiosis I) [p < 0.001 (6/35: RAD24; RAD55; XRS2; TOP3; RAD52; RAD17)]
"Progression through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process)
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase)
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0007126 (meiosis) [p < 0.001 (7/68: RAD24; RAD55; XRS2; TOP3; RAD52; RAD17; DDC1)]
"Progression through meiosis, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiosis occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0007049 (cell cycle)
"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division."
GO:0051321 (meiotic cell cycle) [p < 0.001 (7/68: RAD24; RAD55; XRS2; TOP3; RAD52; RAD17; DDC1)]
"Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process)
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase)
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0000279 (M phase) [p = 0.006 (7/121: RAD24; RAD55; XRS2; TOP3; RAD52; RAD17; DDC1)]
"Progression through M phase, the part of the cell cycle comprising nuclear division."
GO:0051327 (M phase of meiotic cell cycle) [p < 0.001 (7/68: RAD24; RAD55; XRS2; TOP3; RAD52; RAD17; DDC1)]
"Progression through M phase, the part of the meiotic cell cycle during which meiosis takes place."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding)
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding) [p < 0.001 (7/88: RAD18; XRS2; RAD54; TOP3; RAD52; RAD17; RMI1)]
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p < 0.001 (5/19: RAD18; XRS2; RAD52; RAD17; RMI1)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0003697 (single-stranded DNA binding) [p < 0.001 (4/14: RAD18; XRS2; RAD52; RMI1)]
"Interacting selectively with single-stranded DNA."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0043226 (organelle)
"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."
GO:0043228 (non-membrane-bound organelle)
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0043232 (intracellular non-membrane-bound organelle)
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0005694 (chromosome) [p = 0.006 (6/80: RAD18; RAD24; TOP3; RAD52; RMI1; DDC1)]
"A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding)
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding) [p < 0.001 (7/88: RAD18; XRS2; RAD54; TOP3; RAD52; RAD17; RMI1)]
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p < 0.001 (5/19: RAD18; XRS2; RAD52; RAD17; RMI1)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0003690 (double-stranded DNA binding) [p = 0.008 (3/9: XRS2; RAD52; RAD17)]
"Interacting selectively with double-stranded DNA."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (13/384: MSI1; RAD18; RAD24; MET18; RAD55; RAD9; XRS2; RAD54; TOP3; RAD52; RAD17; BRO1; DDC1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (8/62: RAD24; RAD55; XRS2; RAD54; TOP3; RAD52; RAD17; DDC1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006312 (mitotic recombination)
"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles."
GO:0007534 (gene conversion at mating-type locus) [p = 0.009 (3/10: RAD55; RAD54; RAD52)]
"The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (13/384: MSI1; RAD18; RAD24; MET18; RAD55; RAD9; XRS2; RAD54; TOP3; RAD52; RAD17; BRO1; DDC1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (8/62: RAD24; RAD55; XRS2; RAD54; TOP3; RAD52; RAD17; DDC1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0000725 (recombinational repair) [p < 0.001 (5/18: RAD55; XRS2; RAD54; RAD52; DDC1)]
"The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA."
GO:0000724 (double-strand break repair via homologous recombination) [p < 0.001 (4/16: RAD55; XRS2; RAD54; RAD52)]
"The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."
GO:0045003 (double-strand break repair via synthesis-dependent strand annealing) [p = 0.009 (3/10: RAD55; RAD54; RAD52)]
"SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."
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