Genes in this set(11):
| Std. name | Sys. name | SGDID |
| PBY1 | YBR094W | S000000298 |
| MMS4 | YBR098W | S000000302 |
| IML3 | YBR107C | S000000311 |
| SLX1 | YBR228W | S000000432 |
| RRM3 | YHR031C | S000001073 |
| WSS1 | YHR134W | S000001176 |
| MUS81 | YDR386W | S000002794 |
| POL32 | YJR043C | S000003804 |
| SLX4 | YLR135W | S000004125 |
| PIF1 | YML061C | S000004526 |
| PUB1 | YNL016W | S000004961 |
Enriched GO terms in this set:
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003824 (catalytic activity)
"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."
GO:0016787 (hydrolase activity)
"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."
GO:0016788 (hydrolase activity, acting on ester bonds)
"Catalysis of the hydrolysis of any ester bond."
GO:0004518 (nuclease activity) [p = 0.005 (4/28: MMS4; SLX1; MUS81; SLX4)]
"Catalysis of the hydrolysis of ester linkages within nucleic acids."
GO:0004519 (endonuclease activity) [p = 0.001 (4/19: MMS4; SLX1; MUS81; SLX4)]
"Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks."
GO:0004520 (endodeoxyribonuclease activity) [p = 0.001 (4/15: MMS4; SLX1; MUS81; SLX4)]
"Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part)
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0000228 (nuclear chromosome) [p = 0.005 (5/59: IML3; SLX1; RRM3; POL32; SLX4)]
"A chromosome found in the nucleus of a eukaryotic cell."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003824 (catalytic activity)
"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."
GO:0016787 (hydrolase activity)
"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."
GO:0016788 (hydrolase activity, acting on ester bonds)
"Catalysis of the hydrolysis of any ester bond."
GO:0004518 (nuclease activity) [p = 0.005 (4/28: MMS4; SLX1; MUS81; SLX4)]
"Catalysis of the hydrolysis of ester linkages within nucleic acids."
GO:0004519 (endonuclease activity) [p = 0.001 (4/19: MMS4; SLX1; MUS81; SLX4)]
"Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks."
GO:0004520 (endodeoxyribonuclease activity) [p = 0.001 (4/15: MMS4; SLX1; MUS81; SLX4)]
"Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."
GO:0016889 (endodeoxyribonuclease activity, producing 3'-phosphomonoesters)
"Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters."
GO:0008821 (crossover junction endodeoxyribonuclease activity) [p = 0.010 (2/2: MMS4; MUS81)]
"Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044427 (chromosomal part) [p = 0.005 (5/64: IML3; SLX1; RRM3; POL32; SLX4)]
"Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information."
GO:0044454 (nuclear chromosome part) [p = 0.001 (5/44: IML3; SLX1; RRM3; POL32; SLX4)]
"Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell."
GO:0033557 (Slx1-Slx4 complex) [p = 0.010 (2/2: SLX1; SLX4)]
"A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0032991 (macromolecular complex)
"A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together."
GO:0043234 (protein complex)
"Any protein group composed of two or more subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups."
GO:0048476 (Holliday junction resolvase complex) [p = 0.010 (2/2: MMS4; MUS81)]
"A protein complex that mediates the conversion of a Holliday junction into two separate duplex DNA molecules; the complex includes a single- or multisubunit helicase that catalyzes the extension of heteroduplex DNA by branch migration and a nuclease that resolves the junction by nucleolytic cleavage."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0050896 (response to stimulus)
"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus."
GO:0009719 (response to endogenous stimulus) [p = 0.010 (6/123: MMS4; SLX1; WSS1; MUS81; POL32; SLX4)]
"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endogenous stimulus."
GO:0006974 (response to DNA damage stimulus) [p = 0.010 (6/120: MMS4; SLX1; WSS1; MUS81; POL32; SLX4)]
"A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism."
---