Genes in this set(25):
| Std. name | Sys. name | SGDID |
| HIR1 | YBL008W | S000000104 |
| THI2 | YBR240C | S000000444 |
| RAD18 | YCR066W | S000000662 |
| CSM1 | YCR086W | S000000682 |
| RAD51 | YER095W | S000000897 |
| SOD2 | YHR008C | S000001050 |
| RTT107 | YHR154W | S000001197 |
| MLP2 | YIL149C | S000001411 |
| LHP1 | YDL051W | S000002209 |
| RAD55 | YDR076W | S000002483 |
| DPB4 | YDR121W | S000002528 |
| NUP42 | YDR192C | S000002600 |
| XRS2 | YDR369C | S000002777 |
| LRS4 | YDR439W | S000002847 |
| RAD54 | YGL163C | S000003131 |
| SLX9 | YGR081C | S000003313 |
| YOR1 | YGR281W | S000003513 |
| ASF1 | YJL115W | S000003651 |
| MEC3 | YLR288C | S000004279 |
| RAD52 | YML032C | S000004494 |
| PML39 | YML107C | S000004575 |
| MRE11 | YMR224C | S000004837 |
| HIR2 | YOR038C | S000005564 |
| GLR1 | YPL091W | S000006012 |
| MMS1 | YPR164W | S000006368 |
Enriched GO terms in this set:
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0043226 (organelle)
"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."
GO:0043227 (membrane-bound organelle)
"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane."
GO:0043231 (intracellular membrane-bound organelle)
"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane."
GO:0005634 (nucleus) [p < 0.001 (22/570: HIR1; THI2; RAD18; CSM1; RAD51; RTT107; MLP2; LHP1; RAD55; DPB4; NUP42; XRS2; LRS4; RAD54; SLX9; ASF1; MEC3; RAD52; PML39; MRE11; HIR2; GLR1)]
"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part) [p < 0.001 (17/304: HIR1; RAD18; CSM1; RAD51; MLP2; LHP1; RAD55; DPB4; NUP42; XRS2; LRS4; SLX9; ASF1; RAD52; PML39; MRE11; HIR2)]
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (21/568: HIR1; THI2; RAD18; CSM1; RAD51; RTT107; MLP2; LHP1; RAD55; DPB4; XRS2; LRS4; RAD54; SLX9; YOR1; ASF1; MEC3; RAD52; MRE11; HIR2; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (17/384: HIR1; RAD18; CSM1; RAD51; RTT107; RAD55; DPB4; XRS2; LRS4; RAD54; YOR1; ASF1; MEC3; RAD52; MRE11; HIR2; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (9/62: RAD51; RTT107; RAD55; XRS2; RAD54; MEC3; RAD52; MRE11; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0000725 (recombinational repair) [p < 0.001 (6/18: RAD51; RAD55; XRS2; RAD54; RAD52; MRE11)]
"The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA."
GO:0000724 (double-strand break repair via homologous recombination) [p < 0.001 (6/16: RAD51; RAD55; XRS2; RAD54; RAD52; MRE11)]
"The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."
GO:0045003 (double-strand break repair via synthesis-dependent strand annealing) [p < 0.001 (5/10: RAD51; RAD55; RAD54; RAD52; MRE11)]
"SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process)
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase)
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0007127 (meiosis I) [p < 0.001 (7/35: CSM1; RAD51; RAD55; XRS2; LRS4; RAD52; MRE11)]
"Progression through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0016043 (cellular component organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component; includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
GO:0022607 (cellular component assembly)
"A cellular process that results in the assembly of a part of the cell."
GO:0065003 (macromolecular complex assembly)
"The aggregation, arrangement and bonding together of a set of macromolecules to form a complex."
GO:0065004 (protein-DNA complex assembly) [p < 0.001 (5/16: HIR1; RAD55; ASF1; RAD52; HIR2)]
"The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (21/568: HIR1; THI2; RAD18; CSM1; RAD51; RTT107; MLP2; LHP1; RAD55; DPB4; XRS2; LRS4; RAD54; SLX9; YOR1; ASF1; MEC3; RAD52; MRE11; HIR2; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (17/384: HIR1; RAD18; CSM1; RAD51; RTT107; RAD55; DPB4; XRS2; LRS4; RAD54; YOR1; ASF1; MEC3; RAD52; MRE11; HIR2; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (9/62: RAD51; RTT107; RAD55; XRS2; RAD54; MEC3; RAD52; MRE11; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006312 (mitotic recombination) [p = 0.001 (5/18: RAD51; RAD55; RAD54; MEC3; RAD52)]
"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles."
GO:0000722 (telomere maintenance via recombination) [p = 0.001 (4/8: RAD51; RAD54; MEC3; RAD52)]
"The maintenance of proper telomeric length by recombinational processes."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (21/568: HIR1; THI2; RAD18; CSM1; RAD51; RTT107; MLP2; LHP1; RAD55; DPB4; XRS2; LRS4; RAD54; SLX9; YOR1; ASF1; MEC3; RAD52; MRE11; HIR2; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (17/384: HIR1; RAD18; CSM1; RAD51; RTT107; RAD55; DPB4; XRS2; LRS4; RAD54; YOR1; ASF1; MEC3; RAD52; MRE11; HIR2; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (9/62: RAD51; RTT107; RAD55; XRS2; RAD54; MEC3; RAD52; MRE11; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006312 (mitotic recombination) [p = 0.001 (5/18: RAD51; RAD55; RAD54; MEC3; RAD52)]
"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles."
GO:0007534 (gene conversion at mating-type locus) [p = 0.002 (4/10: RAD51; RAD55; RAD54; RAD52)]
"The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003824 (catalytic activity)
"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."
GO:0016787 (hydrolase activity)
"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."
GO:0016817 (hydrolase activity, acting on acid anhydrides)
"Catalysis of the hydrolysis of any acid anhydride."
GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)
"Catalysis of the hydrolysis of any acid anhydride which contains phosphorus."
GO:0016462 (pyrophosphatase activity)
"Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments."
GO:0017111 (nucleoside-triphosphatase activity)
"Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate."
GO:0016887 (ATPase activity)
"Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction."
GO:0042623 (ATPase activity, coupled)
"Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane."
GO:0008094 (DNA-dependent ATPase activity) [p = 0.006 (4/11: RAD18; RAD51; RAD55; RAD54)]
"Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction."
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