Genes in this set(33):
| Std. name | Sys. name | SGDID |
| PIM1 | YBL022C | S000000118 |
| RAD18 | YCR066W | S000000662 |
| | YEL007W | S000000733 |
| RAD51 | YER095W | S000000897 |
| SOD2 | YHR008C | S000001050 |
| STB5 | YHR178W | S000001221 |
| GND1 | YHR183W | S000001226 |
| MPH1 | YIR002C | S000001441 |
| | YDR065W | S000002472 |
| RAD55 | YDR076W | S000002483 |
| ATP5 | YDR298C | S000002706 |
| PEP7 | YDR323C | S000002731 |
| XRS2 | YDR369C | S000002777 |
| RAD54 | YGL163C | S000003131 |
| YOR1 | YGR281W | S000003513 |
| VPS53 | YJL029C | S000003566 |
| RTT101 | YJL047C | S000003583 |
| GON7 | YJL184W | S000003720 |
| RCY1 | YJL204C | S000003740 |
| MOG1 | YJR074W | S000003835 |
| MEC3 | YLR288C | S000004279 |
| VPS33 | YLR396C | S000004388 |
| VPS36 | YLR417W | S000004409 |
| RAD52 | YML032C | S000004494 |
| MRE11 | YMR224C | S000004837 |
| | YNL086W | S000005030 |
| RAD50 | YNL250W | S000005194 |
| SNF8 | YPL002C | S000005923 |
| ATP4 | YPL078C | S000005999 |
| BRO1 | YPL084W | S000006005 |
| GLR1 | YPL091W | S000006012 |
| MSY1 | YPL097W | S000006018 |
| MMS1 | YPR164W | S000006368 |
Enriched GO terms in this set:
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (10/62: RAD51; RAD55; XRS2; RAD54; RTT101; MEC3; RAD52; MRE11; RAD50; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0000725 (recombinational repair) [p < 0.001 (7/18: RAD51; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50)]
"The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA."
GO:0000724 (double-strand break repair via homologous recombination) [p < 0.001 (7/16: RAD51; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50)]
"The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."
GO:0045003 (double-strand break repair via synthesis-dependent strand annealing) [p < 0.001 (6/10: RAD51; RAD55; RAD54; RAD52; MRE11; RAD50)]
"SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (10/62: RAD51; RAD55; XRS2; RAD54; RTT101; MEC3; RAD52; MRE11; RAD50; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006312 (mitotic recombination) [p = 0.002 (6/18: RAD51; RAD55; RAD54; MEC3; RAD52; RAD50)]
"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles."
GO:0000722 (telomere maintenance via recombination) [p < 0.001 (5/8: RAD51; RAD54; MEC3; RAD52; RAD50)]
"The maintenance of proper telomeric length by recombinational processes."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (10/62: RAD51; RAD55; XRS2; RAD54; RTT101; MEC3; RAD52; MRE11; RAD50; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0000725 (recombinational repair) [p < 0.001 (7/18: RAD51; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50)]
"The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA."
GO:0000724 (double-strand break repair via homologous recombination) [p < 0.001 (7/16: RAD51; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50)]
"The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."
GO:0000727 (double-strand break repair via break-induced replication) [p = 0.003 (4/6: XRS2; RAD52; MRE11; RAD50)]
"The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (10/62: RAD51; RAD55; XRS2; RAD54; RTT101; MEC3; RAD52; MRE11; RAD50; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006311 (meiotic gene conversion) [p = 0.003 (5/14: RAD55; XRS2; RAD52; MRE11; RAD50)]
"The cell cycle process whereby genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding)
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding)
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p = 0.002 (6/19: RAD18; XRS2; GON7; RAD52; MRE11; RAD50)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0003690 (double-stranded DNA binding) [p = 0.005 (4/9: XRS2; RAD52; MRE11; RAD50)]
"Interacting selectively with double-stranded DNA."
GO:0003691 (double-stranded telomeric DNA binding) [p = 0.004 (3/3: XRS2; MRE11; RAD50)]
"Interacting selectively with double-stranded telomere-associated DNA."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part)
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0030870 (Mre11 complex) [p = 0.004 (3/3: XRS2; MRE11; RAD50)]
"Trimeric protein complex that possesses endonuclease activity; involved in DNA repair and checkpoint signaling. In Saccharomyces the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins related to the Saccharomyces proteins."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding)
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding)
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p = 0.002 (6/19: RAD18; XRS2; GON7; RAD52; MRE11; RAD50)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0003697 (single-stranded DNA binding) [p = 0.003 (5/14: RAD18; XRS2; RAD52; MRE11; RAD50)]
"Interacting selectively with single-stranded DNA."
GO:0043047 (single-stranded telomeric DNA binding) [p = 0.004 (3/3: XRS2; MRE11; RAD50)]
"Interacting selectively with single-stranded telomere-associated DNA."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding)
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding)
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p = 0.002 (6/19: RAD18; XRS2; GON7; RAD52; MRE11; RAD50)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0051880 (G-quadruplex DNA binding) [p = 0.004 (3/3: XRS2; MRE11; RAD50)]
"Interacting selectively with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (10/62: RAD51; RAD55; XRS2; RAD54; RTT101; MEC3; RAD52; MRE11; RAD50; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0007131 (meiotic recombination) [p = 0.005 (6/28: RAD51; RAD55; XRS2; RAD52; MRE11; RAD50)]
"The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process)
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process)
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (10/62: RAD51; RAD55; XRS2; RAD54; RTT101; MEC3; RAD52; MRE11; RAD50; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006312 (mitotic recombination) [p = 0.002 (6/18: RAD51; RAD55; RAD54; MEC3; RAD52; RAD50)]
"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles."
GO:0007534 (gene conversion at mating-type locus) [p = 0.007 (4/10: RAD51; RAD55; RAD54; RAD52)]
"The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged."
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