Genes in this set(20):
| Std. name | Sys. name | SGDID |
| YSA1 | YBR111C | S000000315 |
| SSH1 | YBR283C | S000000487 |
| | YEL048C | S000000774 |
| GLO3 | YER122C | S000000924 |
| PPA1 | YHR026W | S000001068 |
| AGE2 | YIL044C | S000001306 |
| SEC28 | YIL076W | S000001338 |
| VMA5 | YKL080W | S000001563 |
| VMA10 | YHR039C-A | S000002100 |
| IWR1 | YDL115C | S000002273 |
| ERV14 | YGL054C | S000003022 |
| COG1 | YGL223C | S000003191 |
| VMA7 | YGR020C | S000003252 |
| CAX4 | YGR036C | S000003268 |
| PHO86 | YJL117W | S000003653 |
| | YJL123C | S000003659 |
| | YLR065C | S000004055 |
| LIP2 | YLR239C | S000004229 |
| VMA6 | YLR447C | S000004439 |
| RCE1 | YMR274C | S000004887 |
Enriched GO terms in this set:
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005215 (transporter activity)
"Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells."
GO:0022857 (transmembrane transporter activity)
"Catalysis of the transfer of a substance from one side of a membrane to the other."
GO:0022891 (substrate-specific transmembrane transporter activity)
"Catalysis of the transfer of a specific substance or group of related substances from one side of a membrane to the other."
GO:0015075 (ion transmembrane transporter activity)
"Catalysis of the transfer of an ion from one side of a membrane to the other."
GO:0008324 (cation transmembrane transporter activity)
"Catalysis of the transfer of cation from one side of the membrane to the other."
GO:0022890 (inorganic cation transmembrane transporter activity) [p = 0.001 (5/32: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."
GO:0015077 (monovalent inorganic cation transmembrane transporter activity) [p < 0.001 (5/17: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."
GO:0015078 (hydrogen ion transmembrane transporter activity) [p < 0.001 (5/14: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Catalysis of the transfer of hydrogen ions from one side of a membrane to the other."
GO:0046961 (hydrogen ion transporting ATPase activity, rotational mechanism) [p < 0.001 (5/13: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044464 (cell part)
"Any constituent part of a cell, the basic structural and functional unit of all organisms."
GO:0044425 (membrane part) [p = 0.001 (11/225: SSH1; GLO3; PPA1; SEC28; VMA5; VMA10; ERV14; VMA7; CAX4; VMA6; RCE1)]
"Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins."
GO:0016469 (proton-transporting two-sector ATPase complex) [p = 0.001 (5/19: PPA1; VMA5; VMA10; VMA7; VMA6)]
"A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible."
GO:0033176 (proton-transporting V-type ATPase complex) [p < 0.001 (5/14: PPA1; VMA5; VMA10; VMA7; VMA6)]
"A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane."
GO:0016471 (vacuolar proton-transporting V-type ATPase complex) [p < 0.001 (5/14: PPA1; VMA5; VMA10; VMA7; VMA6)]
"A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0065007 (biological regulation)
"Any process that modulates the frequency, rate or extent of any biological process, quality or function."
GO:0065008 (regulation of biological quality)
"Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc."
GO:0042592 (homeostatic process)
"The biological processes involved in the maintenance of an internal equilibrium."
GO:0048878 (chemical homeostasis)
"The biological processes involved in the maintenance of an internal equilibrium of a chemical."
GO:0050801 (ion homeostasis)
"Any of the processes involved in the maintenance of an internal equilibrium of ions within an organism or cell."
GO:0055080 (cation homeostasis)
"The regulation of the levels, transport, and metabolism of cations."
GO:0055067 (monovalent inorganic cation homeostasis) [p = 0.001 (5/28: PPA1; VMA5; VMA10; VMA7; VMA6)]
"The regulation of the levels, transport, and metabolism of monovalent inorganic cations."
GO:0006885 (regulation of pH) [p = 0.001 (5/23: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Any process that modulates the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion."
GO:0030641 (regulation of cellular pH) [p = 0.001 (5/22: PPA1; VMA5; VMA10; VMA7; VMA6)]
"The regulation of the levels, transport, and metabolism of hydrogen ions (protons) within a cell or between a cell and its external environment."
GO:0051453 (regulation of intracellular pH) [p = 0.001 (5/22: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion."
GO:0051452 (intracellular pH reduction) [p = 0.001 (5/21: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion."
GO:0007035 (vacuolar acidification) [p = 0.001 (5/21: PPA1; VMA5; VMA10; VMA7; VMA6)]
"Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0031090 (organelle membrane) [p = 0.001 (11/232: SSH1; GLO3; PPA1; SEC28; VMA5; VMA10; ERV14; VMA7; CAX4; VMA6; RCE1)]
"The lipid bilayer surrounding an organelle."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003824 (catalytic activity)
"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."
GO:0016787 (hydrolase activity)
"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."
GO:0016817 (hydrolase activity, acting on acid anhydrides) [p = 0.010 (7/89: YSA1; PPA1; VMA5; VMA10; VMA7; CAX4; VMA6)]
"Catalysis of the hydrolysis of any acid anhydride."
GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides) [p = 0.010 (7/89: YSA1; PPA1; VMA5; VMA10; VMA7; CAX4; VMA6)]
"Catalysis of the hydrolysis of any acid anhydride which contains phosphorus."
GO:0016462 (pyrophosphatase activity) [p = 0.010 (7/89: YSA1; PPA1; VMA5; VMA10; VMA7; CAX4; VMA6)]
"Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments."
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