Genes in this set(29):
| Std. name | Sys. name | SGDID |
| RAD18 | YCR066W | S000000662 |
| CSM1 | YCR086W | S000000682 |
| RAD51 | YER095W | S000000897 |
| RAD24 | YER173W | S000000975 |
| SOD2 | YHR008C | S000001050 |
| MET18 | YIL128W | S000001390 |
| MLP2 | YIL149C | S000001411 |
| RAD57 | YDR004W | S000002411 |
| RAD55 | YDR076W | S000002483 |
| NUP42 | YDR192C | S000002600 |
| XRS2 | YDR369C | S000002777 |
| LRS4 | YDR439W | S000002847 |
| RAD54 | YGL163C | S000003131 |
| SLX9 | YGR081C | S000003313 |
| YOR1 | YGR281W | S000003513 |
| RTT101 | YJL047C | S000003583 |
| ASF1 | YJL115W | S000003651 |
| RAD5 | YLR032W | S000004022 |
| TOP3 | YLR234W | S000004224 |
| MEC3 | YLR288C | S000004279 |
| RAD52 | YML032C | S000004494 |
| SML1 | YML058W | S000004523 |
| PML39 | YML107C | S000004575 |
| MRE11 | YMR224C | S000004837 |
| RAD50 | YNL250W | S000005194 |
| RAD17 | YOR368W | S000005895 |
| GLR1 | YPL091W | S000006012 |
| DDC1 | YPL194W | S000006115 |
| MMS1 | YPR164W | S000006368 |
Enriched GO terms in this set:
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process) [p < 0.001 (15/192: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase) [p < 0.001 (14/162: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0007127 (meiosis I) [p < 0.001 (12/35: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; TOP3; RAD52; MRE11; RAD50; RAD17)]
"Progression through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (24/568: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; XRS2; LRS4; RAD54; SLX9; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (22/384: RAD18; CSM1; RAD51; RAD24; MET18; RAD57; RAD55; XRS2; LRS4; RAD54; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (15/62: RAD51; RAD24; RAD57; RAD55; XRS2; RAD54; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0007131 (meiotic recombination) [p < 0.001 (10/28: RAD51; RAD24; RAD57; RAD55; XRS2; TOP3; RAD52; MRE11; RAD50; RAD17)]
"The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process) [p < 0.001 (15/192: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase) [p < 0.001 (14/162: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0007126 (meiosis) [p < 0.001 (13/68: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; TOP3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"Progression through meiosis, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiosis occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0007049 (cell cycle) [p < 0.001 (15/198: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division."
GO:0051321 (meiotic cell cycle) [p < 0.001 (13/68: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; TOP3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process) [p < 0.001 (15/192: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase) [p < 0.001 (14/162: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0000279 (M phase) [p < 0.001 (14/121: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; RTT101; TOP3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"Progression through M phase, the part of the cell cycle comprising nuclear division."
GO:0051327 (M phase of meiotic cell cycle) [p < 0.001 (13/68: CSM1; RAD51; RAD24; RAD57; RAD55; XRS2; LRS4; TOP3; RAD52; MRE11; RAD50; RAD17; DDC1)]
"Progression through M phase, the part of the meiotic cell cycle during which meiosis takes place."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (24/568: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; XRS2; LRS4; RAD54; SLX9; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (22/384: RAD18; CSM1; RAD51; RAD24; MET18; RAD57; RAD55; XRS2; LRS4; RAD54; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (15/62: RAD51; RAD24; RAD57; RAD55; XRS2; RAD54; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0000725 (recombinational repair) [p < 0.001 (9/18: RAD51; RAD57; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50; DDC1)]
"The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA."
GO:0000724 (double-strand break repair via homologous recombination) [p < 0.001 (8/16: RAD51; RAD57; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50)]
"The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."
GO:0045003 (double-strand break repair via synthesis-dependent strand annealing) [p < 0.001 (7/10: RAD51; RAD57; RAD55; RAD54; RAD52; MRE11; RAD50)]
"SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (24/568: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; XRS2; LRS4; RAD54; SLX9; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (22/384: RAD18; CSM1; RAD51; RAD24; MET18; RAD57; RAD55; XRS2; LRS4; RAD54; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0032200 (telomere organization and biogenesis) [p = 0.001 (13/191: CSM1; RAD51; MET18; RAD57; XRS2; RAD54; YOR1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50)]
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that includes the telomeric DNA repeats and associated proteins."
GO:0000723 (telomere maintenance) [p = 0.001 (13/191: CSM1; RAD51; MET18; RAD57; XRS2; RAD54; YOR1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50)]
"The maintenance of proper telomeric length and structure by processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA. These processes includes those that shorten and lengthen the telomeric DNA sequences."
GO:0000722 (telomere maintenance via recombination) [p < 0.001 (6/8: RAD51; RAD57; RAD54; MEC3; RAD52; RAD50)]
"The maintenance of proper telomeric length by recombinational processes."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0043226 (organelle)
"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."
GO:0043227 (membrane-bound organelle)
"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane."
GO:0043231 (intracellular membrane-bound organelle)
"Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane."
GO:0005634 (nucleus) [p < 0.001 (26/570: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; NUP42; XRS2; LRS4; RAD54; SLX9; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; SML1; PML39; MRE11; RAD50; RAD17; GLR1; DDC1)]
"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (24/568: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; XRS2; LRS4; RAD54; SLX9; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (22/384: RAD18; CSM1; RAD51; RAD24; MET18; RAD57; RAD55; XRS2; LRS4; RAD54; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (15/62: RAD51; RAD24; RAD57; RAD55; XRS2; RAD54; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006311 (meiotic gene conversion) [p < 0.001 (6/14: RAD57; RAD55; XRS2; RAD52; MRE11; RAD50)]
"The cell cycle process whereby genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (24/568: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; XRS2; LRS4; RAD54; SLX9; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (22/384: RAD18; CSM1; RAD51; RAD24; MET18; RAD57; RAD55; XRS2; LRS4; RAD54; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (15/62: RAD51; RAD24; RAD57; RAD55; XRS2; RAD54; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0006312 (mitotic recombination) [p < 0.001 (7/18: RAD51; RAD57; RAD55; RAD54; MEC3; RAD52; RAD50)]
"The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles."
GO:0007534 (gene conversion at mating-type locus) [p < 0.001 (5/10: RAD51; RAD57; RAD55; RAD54; RAD52)]
"The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (24/568: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; XRS2; LRS4; RAD54; SLX9; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (22/384: RAD18; CSM1; RAD51; RAD24; MET18; RAD57; RAD55; XRS2; LRS4; RAD54; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0030491 (heteroduplex formation) [p < 0.001 (4/5: RAD51; RAD57; RAD55; RAD54)]
"The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003824 (catalytic activity)
"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."
GO:0016787 (hydrolase activity)
"Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."
GO:0016817 (hydrolase activity, acting on acid anhydrides)
"Catalysis of the hydrolysis of any acid anhydride."
GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)
"Catalysis of the hydrolysis of any acid anhydride which contains phosphorus."
GO:0016462 (pyrophosphatase activity)
"Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments."
GO:0017111 (nucleoside-triphosphatase activity)
"Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate."
GO:0016887 (ATPase activity) [p < 0.001 (8/56: RAD18; RAD51; RAD57; RAD55; RAD54; YOR1; RAD5; RAD50)]
"Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction."
GO:0042623 (ATPase activity, coupled) [p = 0.008 (6/38: RAD18; RAD51; RAD57; RAD55; RAD54; YOR1)]
"Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane."
GO:0008094 (DNA-dependent ATPase activity) [p < 0.001 (5/11: RAD18; RAD51; RAD57; RAD55; RAD54)]
"Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0044237 (cellular metabolic process)
"The chemical reactions and pathways by which individual cells transform chemical substances."
GO:0006139 (nucleobase, nucleoside, nucleotide and nucleic acid metabolic process) [p < 0.001 (24/568: RAD18; CSM1; RAD51; RAD24; MET18; MLP2; RAD57; RAD55; XRS2; LRS4; RAD54; SLX9; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids."
GO:0006259 (DNA metabolic process) [p < 0.001 (22/384: RAD18; CSM1; RAD51; RAD24; MET18; RAD57; RAD55; XRS2; LRS4; RAD54; YOR1; RTT101; ASF1; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides."
GO:0006310 (DNA recombination) [p < 0.001 (15/62: RAD51; RAD24; RAD57; RAD55; XRS2; RAD54; RTT101; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17; DDC1; MMS1)]
"The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction."
GO:0000725 (recombinational repair) [p < 0.001 (9/18: RAD51; RAD57; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50; DDC1)]
"The repair of damaged DNA that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA."
GO:0000724 (double-strand break repair via homologous recombination) [p < 0.001 (8/16: RAD51; RAD57; RAD55; XRS2; RAD54; RAD52; MRE11; RAD50)]
"The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule."
GO:0000727 (double-strand break repair via break-induced replication) [p < 0.001 (4/6: XRS2; RAD52; MRE11; RAD50)]
"The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0022414 (reproductive process)
"A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents."
GO:0003006 (reproductive developmental process) [p < 0.001 (5/15: RAD51; RAD57; RAD55; RAD54; RAD52)]
"A developmental process by which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring."
GO:0007530 (sex determination) [p < 0.001 (5/15: RAD51; RAD57; RAD55; RAD54; RAD52)]
"Any process that establishes and transmits the specification of sexual status of an individual organism."
GO:0007531 (mating type determination) [p < 0.001 (5/15: RAD51; RAD57; RAD55; RAD54; RAD52)]
"Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms."
GO:0007533 (mating type switching) [p < 0.001 (5/15: RAD51; RAD57; RAD55; RAD54; RAD52)]
"The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0043226 (organelle)
"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."
GO:0043228 (non-membrane-bound organelle)
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0043232 (intracellular non-membrane-bound organelle)
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0005694 (chromosome) [p < 0.001 (9/80: RAD18; CSM1; RAD51; RAD24; LRS4; RAD5; TOP3; RAD52; DDC1)]
"A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0016043 (cellular component organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component; includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
GO:0022607 (cellular component assembly)
"A cellular process that results in the assembly of a part of the cell."
GO:0065003 (macromolecular complex assembly)
"The aggregation, arrangement and bonding together of a set of macromolecules to form a complex."
GO:0006461 (protein complex assembly)
"The aggregation, arrangement and bonding together of a set of components to form a protein complex."
GO:0000730 (DNA recombinase assembly) [p < 0.001 (3/3: RAD57; RAD55; RAD52)]
"The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA."
GO:0000707 (meiotic DNA recombinase assembly) [p < 0.001 (3/3: RAD57; RAD55; RAD52)]
"During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding) [p = 0.001 (11/140: RAD18; XRS2; RAD54; SLX9; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding) [p < 0.001 (10/88: RAD18; XRS2; RAD54; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p < 0.001 (7/19: RAD18; XRS2; RAD5; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0003690 (double-stranded DNA binding) [p < 0.001 (5/9: XRS2; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with double-stranded DNA."
GO:0003691 (double-stranded telomeric DNA binding) [p < 0.001 (3/3: XRS2; MRE11; RAD50)]
"Interacting selectively with double-stranded telomere-associated DNA."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044428 (nuclear part) [p < 0.001 (18/304: RAD18; CSM1; RAD51; MET18; MLP2; RAD57; RAD55; NUP42; XRS2; LRS4; SLX9; ASF1; RAD5; RAD52; PML39; MRE11; RAD50; DDC1)]
"Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated."
GO:0030870 (Mre11 complex) [p < 0.001 (3/3: XRS2; MRE11; RAD50)]
"Trimeric protein complex that possesses endonuclease activity; involved in DNA repair and checkpoint signaling. In Saccharomyces the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins related to the Saccharomyces proteins."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding) [p = 0.001 (11/140: RAD18; XRS2; RAD54; SLX9; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding) [p < 0.001 (10/88: RAD18; XRS2; RAD54; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p < 0.001 (7/19: RAD18; XRS2; RAD5; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0003697 (single-stranded DNA binding) [p < 0.001 (6/14: RAD18; XRS2; RAD5; RAD52; MRE11; RAD50)]
"Interacting selectively with single-stranded DNA."
GO:0043047 (single-stranded telomeric DNA binding) [p < 0.001 (3/3: XRS2; MRE11; RAD50)]
"Interacting selectively with single-stranded telomere-associated DNA."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0003676 (nucleic acid binding) [p = 0.001 (11/140: RAD18; XRS2; RAD54; SLX9; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with any nucleic acid."
GO:0003677 (DNA binding) [p < 0.001 (10/88: RAD18; XRS2; RAD54; RAD5; TOP3; MEC3; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with DNA (deoxyribonucleic acid)."
GO:0043566 (structure-specific DNA binding) [p < 0.001 (7/19: RAD18; XRS2; RAD5; RAD52; MRE11; RAD50; RAD17)]
"Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."
GO:0051880 (G-quadruplex DNA binding) [p < 0.001 (3/3: XRS2; MRE11; RAD50)]
"Interacting selectively with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0048468 (cell development) [p = 0.007 (5/22: RAD51; RAD57; RAD55; RAD54; RAD52)]
"The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate."
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