Genes in this set(20):
| Std. name | Sys. name | SGDID |
| SHE1 | YBL031W | S000000127 |
| DCC1 | YCL016C | S000000521 |
| BIK1 | YCL029C | S000000534 |
| ARP1 | YHR129C | S000001171 |
| CTF8 | YHR191C | S000001234 |
| DYN1 | YKR054C | S000001762 |
| FIN1 | YDR130C | S000002537 |
| | YDR149C | S000002556 |
| NUM1 | YDR150W | S000002557 |
| DYN2 | YDR424C | S000002832 |
| PAC11 | YDR488C | S000002896 |
| LDB18 | YLL049W | S000003972 |
| NDL1 | YLR254C | S000004244 |
| CTF18 | YMR078C | S000004683 |
| JNM1 | YMR294W | S000004908 |
| DYN3 | YMR299C | S000004914 |
| KIN4 | YOR233W | S000005759 |
| PAC1 | YOR269W | S000005795 |
| KIP2 | YPL155C | S000006076 |
| NIP100 | YPL174C | S000006095 |
Enriched GO terms in this set:
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0043226 (organelle)
"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."
GO:0043228 (non-membrane-bound organelle) [p < 0.001 (17/276: SHE1; DCC1; BIK1; ARP1; CTF8; DYN1; FIN1; DYN2; PAC11; NDL1; CTF18; JNM1; DYN3; KIN4; PAC1; KIP2; NIP100)]
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0043232 (intracellular non-membrane-bound organelle) [p < 0.001 (17/276: SHE1; DCC1; BIK1; ARP1; CTF8; DYN1; FIN1; DYN2; PAC11; NDL1; CTF18; JNM1; DYN3; KIN4; PAC1; KIP2; NIP100)]
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0005856 (cytoskeleton) [p < 0.001 (14/89: SHE1; BIK1; ARP1; DYN1; FIN1; DYN2; PAC11; NDL1; JNM1; DYN3; KIN4; PAC1; KIP2; NIP100)]
"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles."
GO:0015630 (microtubule cytoskeleton) [p < 0.001 (14/36: SHE1; BIK1; ARP1; DYN1; FIN1; DYN2; PAC11; NDL1; JNM1; DYN3; KIN4; PAC1; KIP2; NIP100)]
"The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0051179 (localization)
"The processes by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location."
GO:0051641 (cellular localization)
"The processes by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell."
GO:0051640 (organelle localization) [p < 0.001 (10/38: ARP1; DYN1; NUM1; PAC11; NDL1; JNM1; DYN3; PAC1; KIP2; NIP100)]
"The processes by which an organelle is transported to, and/or maintained in, a specific location."
GO:0051647 (nucleus localization) [p < 0.001 (9/15: ARP1; DYN1; NUM1; PAC11; NDL1; JNM1; DYN3; PAC1; KIP2)]
"The processes by which the nucleus is transported to, and/or maintained in, a specific location within the cell."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044430 (cytoskeletal part) [p < 0.001 (13/84: BIK1; ARP1; DYN1; FIN1; DYN2; PAC11; NDL1; JNM1; DYN3; KIN4; PAC1; KIP2; NIP100)]
"Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice."
GO:0005874 (microtubule) [p < 0.001 (9/19: BIK1; DYN1; FIN1; DYN2; PAC11; NDL1; DYN3; PAC1; KIP2)]
"Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle."
GO:0005881 (cytoplasmic microtubule) [p < 0.001 (8/12: DYN1; FIN1; DYN2; PAC11; NDL1; DYN3; PAC1; KIP2)]
"Any microtubule in the cytoplasm of a cell."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0051234 (establishment of localization)
"The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location."
GO:0051656 (establishment of organelle localization) [p < 0.001 (10/21: ARP1; DYN1; NUM1; PAC11; NDL1; JNM1; DYN3; PAC1; KIP2; NIP100)]
"The directed movement of an organelle to a specific location."
GO:0040023 (establishment of nucleus localization) [p < 0.001 (9/15: ARP1; DYN1; NUM1; PAC11; NDL1; JNM1; DYN3; PAC1; KIP2)]
"The directed movement of the nucleus to a specific location within a cell."
GO:0007097 (nuclear migration) [p < 0.001 (9/15: ARP1; DYN1; NUM1; PAC11; NDL1; JNM1; DYN3; PAC1; KIP2)]
"The directed movement of the nucleus."
GO:0030473 (nuclear migration, microtubule-mediated) [p < 0.001 (7/12: DYN1; NUM1; PAC11; NDL1; DYN3; PAC1; KIP2)]
"The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0005515 (protein binding)
"Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)."
GO:0008092 (cytoskeletal protein binding) [p = 0.001 (6/36: BIK1; FIN1; NUM1; NDL1; PAC1; NIP100)]
"Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)."
GO:0015631 (tubulin binding) [p < 0.001 (6/17: BIK1; FIN1; NUM1; NDL1; PAC1; NIP100)]
"Interacting selectively with monomeric or multimeric forms of tubulin, including microtubules."
GO:0008017 (microtubule binding) [p < 0.001 (5/8: BIK1; FIN1; NDL1; PAC1; NIP100)]
"Interacting selectively with microtubules, filaments composed of tubulin monomers."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044430 (cytoskeletal part) [p < 0.001 (13/84: BIK1; ARP1; DYN1; FIN1; DYN2; PAC11; NDL1; JNM1; DYN3; KIN4; PAC1; KIP2; NIP100)]
"Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice."
GO:0005875 (microtubule associated complex) [p < 0.001 (8/13: ARP1; DYN1; DYN2; PAC11; JNM1; DYN3; KIP2; NIP100)]
"Any multimeric complex connected to a microtubule."
GO:0030286 (dynein complex) [p < 0.001 (4/4: DYN1; DYN2; PAC11; DYN3)]
"Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity."
GO:0005868 (cytoplasmic dynein complex) [p < 0.001 (4/4: DYN1; DYN2; PAC11; DYN3)]
"Any dynein complex that catalyzes movement along a cytoplasmic microtubule; cytoplasmic dynein complexes participates in many transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes,and may include light chains and light intermediate chains."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0016043 (cellular component organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component; includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
GO:0006996 (organelle organization and biogenesis)
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of any organelle within a cell."
GO:0007010 (cytoskeleton organization and biogenesis) [p < 0.001 (12/108: BIK1; ARP1; DYN1; FIN1; NUM1; DYN2; PAC11; NDL1; DYN3; PAC1; KIP2; NIP100)]
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures."
GO:0007017 (microtubule-based process) [p < 0.001 (12/46: BIK1; ARP1; DYN1; FIN1; NUM1; DYN2; PAC11; NDL1; DYN3; PAC1; KIP2; NIP100)]
"Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins."
GO:0000226 (microtubule cytoskeleton organization and biogenesis) [p < 0.001 (7/32: BIK1; ARP1; DYN1; FIN1; NUM1; KIP2; NIP100)]
"A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0007049 (cell cycle) [p = 0.007 (10/198: DCC1; BIK1; ARP1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2; NIP100)]
"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division."
GO:0000278 (mitotic cell cycle) [p < 0.001 (10/117: DCC1; BIK1; ARP1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2; NIP100)]
"Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process) [p = 0.006 (10/192: DCC1; BIK1; ARP1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2; NIP100)]
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase)
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0007067 (mitosis) [p < 0.001 (8/62: DCC1; BIK1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2)]
"Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process) [p = 0.006 (10/192: DCC1; BIK1; ARP1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2; NIP100)]
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0022403 (cell cycle phase)
"A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events."
GO:0000279 (M phase) [p = 0.008 (8/121: DCC1; BIK1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2)]
"Progression through M phase, the part of the cell cycle comprising nuclear division."
GO:0000087 (M phase of mitotic cell cycle) [p < 0.001 (8/63: DCC1; BIK1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2)]
"Progression through M phase, the part of the mitotic cell cycle during which mitosis takes place."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044430 (cytoskeletal part) [p < 0.001 (13/84: BIK1; ARP1; DYN1; FIN1; DYN2; PAC11; NDL1; JNM1; DYN3; KIN4; PAC1; KIP2; NIP100)]
"Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice."
GO:0005875 (microtubule associated complex) [p < 0.001 (8/13: ARP1; DYN1; DYN2; PAC11; JNM1; DYN3; KIP2; NIP100)]
"Any multimeric complex connected to a microtubule."
GO:0005869 (dynactin complex) [p = 0.001 (3/3: ARP1; JNM1; NIP100)]
"A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044427 (chromosomal part)
"Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information."
GO:0031390 (Ctf18 RFC-like complex) [p = 0.001 (3/3: DCC1; CTF8; CTF18)]
"A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p."
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GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0003774 (motor activity) [p = 0.004 (4/13: DYN1; DYN2; PAC11; KIP2)]
"Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate."
GO:0003777 (microtubule motor activity) [p = 0.001 (4/10: DYN1; DYN2; PAC11; KIP2)]
"Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0022402 (cell cycle process) [p = 0.006 (10/192: DCC1; BIK1; ARP1; CTF8; DYN1; FIN1; CTF18; KIN4; KIP2; NIP100)]
"A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events."
GO:0000819 (sister chromatid segregation) [p = 0.005 (5/30: DCC1; CTF8; DYN1; FIN1; CTF18)]
"The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets."
GO:0000070 (mitotic sister chromatid segregation) [p = 0.004 (5/29: DCC1; CTF8; DYN1; FIN1; CTF18)]
"The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets."
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