Genes in this set(39):
| Std. name | Sys. name | SGDID |
| SPC72 | YAL047C | S000000045 |
| CCZ1 | YBR131W | S000000335 |
| SAT4 | YCR008W | S000000601 |
| HCM1 | YCR065W | S000000661 |
| PAT1 | YCR077C | S000000673 |
| GIM4 | YEL003W | S000000729 |
| CIN8 | YEL061C | S000000787 |
| BIM1 | YER016W | S000000818 |
| BOI2 | YER114C | S000000916 |
| MTG2 | YHR168W | S000001211 |
| CAP2 | YIL034C | S000001296 |
| CAP1 | YKL007W | S000001490 |
| MYO3 | YKL129C | S000001612 |
| RPL34A | YER056C-A | S000002135 |
| | YDL063C | S000002221 |
| BMH2 | YDR099W | S000002506 |
| PPZ2 | YDR436W | S000002844 |
| MON1 | YGL124C | S000003092 |
| KIP3 | YGL216W | S000003184 |
| | YGL217C | S000003185 |
| PAC10 | YGR078C | S000003310 |
| RPS23A | YGR118W | S000003350 |
| YKE2 | YLR200W | S000004190 |
| CLB4 | YLR210W | S000004200 |
| CPR6 | YLR216C | S000004206 |
| ATP10 | YLR393W | S000004385 |
| RPS18B | YML026C | S000004488 |
| GIM5 | YML094W | S000004559 |
| | YML094C-A | S000004561 |
| TUB3 | YML124C | S000004593 |
| GIM3 | YNL153C | S000005097 |
| BNI1 | YNL271C | S000005215 |
| YPT11 | YNL304W | S000005248 |
| ASE1 | YOR058C | S000005584 |
| CIN1 | YOR349W | S000005876 |
| | YPL205C | S000006126 |
| CIN2 | YPL241C | S000006162 |
| KAR9 | YPL269W | S000006190 |
| KAR3 | YPR141C | S000006345 |
Enriched GO terms in this set:
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0008152 (metabolic process)
"Processes that cause many of the chemical changes in living organisms, including anabolism and catabolism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation."
GO:0044238 (primary metabolic process)
"Reactions involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism."
GO:0019538 (protein metabolic process)
"The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification."
GO:0044267 (cellular protein metabolic process)
"The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification."
GO:0006457 (protein folding) [p < 0.001 (8/41: GIM4; PAC10; YKE2; CPR6; GIM5; GIM3; CIN1; CIN2)]
"The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure."
GO:0007021 (tubulin folding) [p < 0.001 (7/11: GIM4; PAC10; YKE2; GIM5; GIM3; CIN1; CIN2)]
"Folding of the microtubule constituent proteins alpha- and beta-tubulin into the native alpha-beta heterodimer."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044464 (cell part)
"Any constituent part of a cell, the basic structural and functional unit of all organisms."
GO:0044424 (intracellular part)
"Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm."
GO:0044444 (cytoplasmic part)
"Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures."
GO:0044445 (cytosolic part) [p = 0.002 (9/64: PAT1; GIM4; RPL34A; PAC10; RPS23A; YKE2; RPS18B; GIM5; GIM3)]
"Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components."
GO:0016272 (prefoldin complex) [p < 0.001 (5/6: GIM4; PAC10; YKE2; GIM5; GIM3)]
"A multisubunit chaperone that acts to delivers unfolded proteins to cytosolic chaperonin. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits."
---
GO:0003674 (molecular_function)
"Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."
GO:0005488 (binding)
"The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."
GO:0005515 (protein binding)
"Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)."
GO:0008092 (cytoskeletal protein binding) [p < 0.001 (10/36: GIM4; CAP2; CAP1; PAC10; YKE2; GIM5; GIM3; BNI1; ASE1; CIN1)]
"Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)."
GO:0015631 (tubulin binding) [p < 0.001 (7/17: GIM4; PAC10; YKE2; GIM5; GIM3; ASE1; CIN1)]
"Interacting selectively with monomeric or multimeric forms of tubulin, including microtubules."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0008152 (metabolic process)
"Processes that cause many of the chemical changes in living organisms, including anabolism and catabolism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation."
GO:0044238 (primary metabolic process)
"Reactions involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism."
GO:0019538 (protein metabolic process)
"The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification."
GO:0044267 (cellular protein metabolic process)
"The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification."
GO:0051261 (protein depolymerization) [p < 0.001 (5/9: BIM1; CAP2; CAP1; KIP3; ASE1)]
"The process by which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0051234 (establishment of localization)
"The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location."
GO:0051656 (establishment of organelle localization) [p < 0.001 (6/21: SPC72; BIM1; KIP3; TUB3; BNI1; KAR9)]
"The directed movement of an organelle to a specific location."
GO:0040023 (establishment of nucleus localization) [p = 0.005 (5/15: SPC72; BIM1; KIP3; TUB3; KAR9)]
"The directed movement of the nucleus to a specific location within a cell."
GO:0007097 (nuclear migration) [p = 0.005 (5/15: SPC72; BIM1; KIP3; TUB3; KAR9)]
"The directed movement of the nucleus."
GO:0030473 (nuclear migration, microtubule-mediated) [p < 0.001 (5/12: SPC72; BIM1; KIP3; TUB3; KAR9)]
"The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins."
---
GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0009987 (cellular process)
"Processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0007049 (cell cycle)
"The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division."
GO:0000278 (mitotic cell cycle) [p = 0.001 (12/117: SPC72; SAT4; HCM1; CIN8; BIM1; BMH2; KIP3; CLB4; TUB3; BNI1; ASE1; KAR3)]
"Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0065007 (biological regulation)
"Any process that modulates the frequency, rate or extent of any biological process, quality or function."
GO:0050789 (regulation of biological process)
"Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule."
GO:0050794 (regulation of cellular process)
"Any process that modulates the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level."
GO:0051128 (regulation of cellular component organization and biogenesis) [p = 0.001 (5/13: BIM1; CAP2; CAP1; BNI1; ASE1)]
"Any process that modulates the frequency, rate or extent of the processes involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
GO:0051129 (negative regulation of cellular component organization and biogenesis) [p = 0.002 (4/7: BIM1; CAP2; CAP1; ASE1)]
"Any process that stops, prevents or reduces the frequency, rate or extent of the processes involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044430 (cytoskeletal part) [p < 0.001 (11/84: SPC72; CIN8; BIM1; CAP2; CAP1; MYO3; KIP3; TUB3; BNI1; ASE1; KAR3)]
"Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice."
GO:0005819 (spindle) [p = 0.002 (6/24: SPC72; CIN8; BIM1; TUB3; ASE1; KAR3)]
"The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart."
---
GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0043226 (organelle)
"Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane."
GO:0043228 (non-membrane-bound organelle)
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0043232 (intracellular non-membrane-bound organelle)
"Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes."
GO:0005856 (cytoskeleton) [p < 0.001 (11/89: SPC72; CIN8; BIM1; CAP2; CAP1; MYO3; KIP3; TUB3; BNI1; ASE1; KAR3)]
"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles."
GO:0015630 (microtubule cytoskeleton) [p = 0.002 (7/36: SPC72; CIN8; BIM1; KIP3; TUB3; ASE1; KAR3)]
"The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044430 (cytoskeletal part) [p < 0.001 (11/84: SPC72; CIN8; BIM1; CAP2; CAP1; MYO3; KIP3; TUB3; BNI1; ASE1; KAR3)]
"Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice."
GO:0005874 (microtubule) [p < 0.001 (6/19: CIN8; BIM1; KIP3; TUB3; ASE1; KAR3)]
"Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle."
GO:0005880 (nuclear microtubule) [p = 0.005 (3/3: KIP3; TUB3; ASE1)]
"Any microtubule in the nucleus of a cell."
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GO:0005575 (cellular_component)
"The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together."
GO:0044422 (organelle part)
"Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane."
GO:0044446 (intracellular organelle part)
"A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane."
GO:0044430 (cytoskeletal part) [p < 0.001 (11/84: SPC72; CIN8; BIM1; CAP2; CAP1; MYO3; KIP3; TUB3; BNI1; ASE1; KAR3)]
"Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice."
GO:0005884 (actin filament) [p = 0.005 (3/3: CAP2; CAP1; BNI1)]
"A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane."
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GO:0008150 (biological_process)
"Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end."
GO:0051179 (localization)
"The processes by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location."
GO:0051641 (cellular localization)
"The processes by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell."
GO:0051640 (organelle localization) [p = 0.005 (7/38: SPC72; BIM1; KIP3; TUB3; BNI1; YPT11; KAR9)]
"The processes by which an organelle is transported to, and/or maintained in, a specific location."
GO:0051647 (nucleus localization) [p = 0.005 (5/15: SPC72; BIM1; KIP3; TUB3; KAR9)]
"The processes by which the nucleus is transported to, and/or maintained in, a specific location within the cell."
---