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Inferred GRN in microglia
Here we provide visualizations of local connectivities at different life stages in mice microglia. The details is described in our paper. We are using the time-series data published by Hammond, 2019.
Reference
Hammond, Timothy R., et al. "Single-cell RNA sequencing of microglia throughout the mouse lifespan and in the injured brain reveals complex cell-state changes." Immunity 50.1 (2019): 253-271.
Hammond, Timothy R., et al. "Single-cell RNA sequencing of microglia throughout the mouse lifespan and in the injured brain reveals complex cell-state changes." Immunity 50.1 (2019): 253-271.
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A few notes before using this tool:
- The dropdown menu includes more than 10,000 genes. If you are looking for specific genes, it might be easier to type in gene names in the input box.
- The small network only includes 10% of links in the large network. Use the large network when your internet speed permits.
- All the links provided here are computed based on the released single cell RNA-seq data. We have not performed lab experiments to validate the links so please digest the info with caution. Please refer to our paper for some literature review we have done that shows the validitiy of some suggested links.